But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Base Information

Chemical Name:But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide
CAS No.:920749-95-7
Molecular Formula:C₂₁H₃₇NO
Molecular Weight:319.531
Hs Code.:

Synonyms:But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Suppliers and Price of But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

There total 3 articles about But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 881920-78-1
(1S,2S,4R)-2-((R,E)-3-isocyanato-3-methylhex-1-enyl)-1-isopropyl-4-methylcyclohexane

: 1730-25-2
allylmagnesium bromide

: 920749-95-7
But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Guidance literature:: In tetrahydrofuran; at 0 ℃;
DOI:10.1016/j.jorganchem.2006.07.028

Reference yield:

: 142921-16-2
(E)-1-iodo-2-methylpent-1-ene

: 920749-95-7
But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-BuLi / diethyl ether; petroleum ether / 0.5 h / -78 °C

1.2: 77 percent / diethyl ether; petroleum ether / -78 °C

2.1: CH₂Cl₂ / 1 h / 0 °C

2.2: potassium carbonate / methanol; H₂O / 0 - 20 °C

2.3: 95 percent / TFAA; triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

3.1: 99 percent / tetrahydrofuran / 0 °C

With n-butyllithium; In tetrahydrofuran; diethyl ether; dichloromethane; Petroleum ether;
DOI:10.1016/j.jorganchem.2006.07.028

Reference yield:

: 881920-66-7
(S,E)-1-((1R,2S,5R)-2-isopropyl-5-methylcyclohexyl)-3-methylhex-2-en-1-ol

: 920749-95-7
But-3-enoic acid {(R)-1-[(E)-2-((1S,2S,5R)-2-isopropyl-5-methyl-cyclohexyl)-vinyl]-1-methyl-butyl}-amide

Guidance literature:: Multi-step reaction with 2 steps

1.1: CH₂Cl₂ / 1 h / 0 °C

1.2: potassium carbonate / methanol; H₂O / 0 - 20 °C

1.3: 95 percent / TFAA; triethylamine / CH₂Cl₂ / 0.25 h / 0 °C

2.1: 99 percent / tetrahydrofuran / 0 °C

In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.jorganchem.2006.07.028