Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate

Base Information

Chemical Name:Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate
CAS No.:151-68-8
Molecular Formula:C24H32O4
Molecular Weight:384.5085
Hs Code.:
UNII:7R029K4C6F
DSSTox Substance ID:DTXSID90934143
Nikkaji Number:J1.188.291I
Wikidata:Q27268729

Synonyms:BRN 2486539;UNII-7R029K4C6F;7R029K4C6F;Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate;151-68-8;17-Hydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione acetate;6-alpha-Methyl-delta(sup 1)-dehydro-17-alpha-acetoxyprogesterone;Pregna-1,4-diene-3,20-dione, 17-(acetyloxy)-6-methyl-, (6-alpha)-;4-08-00-02430 (Beilstein Handbook Reference);17-(Acetyloxy)-6-methyl-pregna-1,4-diene-3,20-dione, (6alpha)-;SCHEMBL6564735;DTXSID90934143;LS-118487;6alpha-Methyl-1,2-didehydro-17-acetoxyprogesterone;6-Methyl-3,20-dioxopregna-1,4-dien-17-yl acetate;Q27268729;(6alpha)-17-(acetyloxy)-6-methyl-pregna-1,4-diene-3,20-dione;(6.ALPHA.)-17-(ACETYLOXY)-6-METHYLPREGNA-1,4-DIENE-3,20-DIONE;17-(ACETYLOXY)-6-METHYL-PREGNA-1,4-DIENE-3,20-DIONE, (6.ALPHA.)-;PREGNA-1,4-DIENE-3,20-DIONE, 17-(ACETYLOXY)-6-METHYL-, (6.ALPHA.)-;PREGNA-1,4-DIENE-3,20-DIONE, 17-HYDROXY-6.ALPHA.-METHYL-, ACETATE

Suppliers and Price of Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate

Chemical Property:

Vapor Pressure:4.7E-10mmHg at 25°C
Boiling Point:498°C at 760 mmHg
Flash Point:214.3°C
Density:1.15g/cm³
XLogP3:4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:384.23005950
Heavy Atom Count:28
Complexity:807

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1CC2C3CCC(C3(CCC2C4(C1=CC(=O)C=C4)C)C)(C(=O)C)OC(=O)C
Isomeric SMILES:C[C@H]1C[C@H]2[C@@H]3CC[C@@]([C@]3(CC[C@@H]2[C@@]4(C1=CC(=O)C=C4)C)C)(C(=O)C)OC(=O)C

Technology Process of Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate

There total 11 articles about Pregna-1,4-diene-3,20-dione, 17-hydroxy-6-alpha-methyl-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 71-58-9
Medroxyprogesterone acetate

: 151-68-8
6α-Methyl-17α-hydroxy-1,4-pregnadien-3,20-dion

Guidance literature:: With pyridine; selenium(IV) oxide; tert-butyl alcohol;
DOI:10.1021/ja01523a055

Reference yield:

: 1863-39-4
3β-acetoxy-17α-hydroxy-5-pregnen-20-one

: 151-68-8
6α-Methyl-17α-hydroxy-1,4-pregnadien-3,20-dion

Guidance literature:: Multi-step reaction with 8 steps

1: benzene; toluene-4-sulfonic acid

2: peroxybenzoic acid; chloroform

3: benzene; diethyl ether

4: aqueous methanol.H₂SO₄

5: CrO₃; pyridine

6: aqueous HCl

7: acetic acid; toluene-4-sulfonic acid

8: SeO₂; pyridine; tert-butyl alcohol

With pyridine; chromium(VI) oxide; hydrogenchloride; selenium(IV) oxide; Perbenzoic acid; diethyl ether; chloroform; sulfuric acid; toluene-4-sulfonic acid; acetic acid; tert-butyl alcohol; benzene;
DOI:10.1021/ja01523a055

Reference yield:

: 520-85-4
Medroxyprogesterone

: 151-68-8
6α-Methyl-17α-hydroxy-1,4-pregnadien-3,20-dion

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; toluene-4-sulfonic acid

2: SeO₂; pyridine; tert-butyl alcohol

With pyridine; selenium(IV) oxide; toluene-4-sulfonic acid; acetic acid; tert-butyl alcohol;
DOI:10.1021/ja01523a055