4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

Base Information Edit

Chemical Name:4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one
CAS No.:15646-46-5
Molecular Formula:C12H11NO3
Molecular Weight:217.224
Hs Code.:29349990
European Community (EC) Number:239-713-9
UNII:40RAK33386
DSSTox Substance ID:DTXSID60860167
Wikidata:Q27258354
Metabolomics Workbench ID:58530
Mol file:15646-46-5.mol

Synonyms:2-Phenyl-4-(ethoxymethylene)oxazol-5-one;4 Ethoxymethylene 2 phenyloxazolone;4-Ethoxymethylene-2-phenyloxazolone;Oxazolone

Suppliers and Price of 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one purified by recrystallization
10 g
$ 327.00

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one purified by recrystallization
10g-a
$ 313.00

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one analytical standard, for drug analysis
1g
$ 41.70

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one purified by recrystallization
1 g
$ 40.70

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one purified by recrystallization
1g-a
$ 39.70

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one analytical standard, for drug analysis
10g
$ 206.00

Sigma-Aldrich
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one analytical standard, for drug analysis
5g
$ 163.00

Matrix Scientific
(4E)-4-(Ethoxymethylene)-2-phenyl-1,3-oxazol-5(4H)-one
500mg
$ 119.00

Crysdot
4-(Ethoxymethylene)-2-phenyloxazol-5(4H)-one 95+%
5g
$ 349.00

Atlantic Research Chemicals
4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one 95%
10gm:
$ 127.24

Total 46 raw suppliers

Chemical Property of 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one Edit

Chemical Property:

Appearance/Colour:White to orange or pink powder
Vapor Pressure:0.000666mmHg at 25°C
Melting Point:94-96 °C (dec.)(lit.)
Refractive Index:1.561
Boiling Point:308.8 °C at 760 mmHg
PKA:-2.59±0.20(Predicted)
Flash Point:136.8 °C
PSA：47.89000
Density:1.18 g/cm³
LogP:1.30350
Storage Temp.:2-8°C
Water Solubility.:Soluble in methanol (50 mg/ml), and water (partly).
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:217.07389321
Heavy Atom Count:16
Complexity:327

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one purified by recrystallization ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 43
Safety Statements: 36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC=C1C(=O)OC(=N1)C2=CC=CC=C2
Isomeric SMILES:CCO/C=C/1\C(=O)OC(=N1)C2=CC=CC=C2
Recent EU Clinical Trials:POST-SURGICAL LIQUID BIOPSY-GUIDED TREATMENT OF STAGE III AND HIGH-RISK STAGE II COLON CANCER PATIENTS
Uses 4-Ethoxymethylene-2-phenyloxazolin-5-one acts as sensitizing agent. It is also used as pharmaceutical intermediates. 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one has been used as a haptenizing agent, which can induce an inflammatory reaction in adult zebrafish intestinal tissues and this can be used as a model for gene expression studies of the two forms of inflammatory bowel disease like Crohn′s disease and ulcerative colitis.

Technology Process of 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one

There total 10 articles about 4-Ethoxymethylene-2-phenyl-2-oxazolin-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%