3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium

Base Information

Chemical Name:3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium
CAS No.:142643-29-6
Molecular Formula:C11H22N2O2
Molecular Weight:214.308
Hs Code.:29333990
DSSTox Substance ID:DTXSID80931565
Wikidata:Q72448243
Mol file:142643-29-6.mol

Synonyms:DTXSID80931565;3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium

Suppliers and Price of 3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-N-Boc-aminomethylPiperidine
250mg
$ 70.00

Synthonix
3-(Boc-aminomethyl)piperidine 95+%
5g
$ 70.00

SynQuest Laboratories
3-(Aminomethyl)piperidine, 3-Boc protected 97%
5 g
$ 104.00

SynQuest Laboratories
3-(Aminomethyl)piperidine, 3-Boc protected 97%
1 g
$ 39.00

SynQuest Laboratories
3-(Aminomethyl)piperidine, 3-Boc protected 97%
25 g
$ 340.00

Sigma-Aldrich
(±)-3-(Boc-aminomethyl)piperidine ≥98.0% (TLC)
500mg-f
$ 109.00

Sigma-Aldrich
3-(Boc-aminomethyl)piperidine 95%
10g
$ 241.00

Sigma-Aldrich
3-(Boc-amino)piperidine 97%
1 g
$ 58.60

Sigma-Aldrich
3-(Boc-aminomethyl)piperidine 95%
1g
$ 44.10

Matrix Scientific
tert-Butyl (piperidin-3-ylmethyl)carbamate 95%
1g
$ 70.00

Total 72 raw suppliers

Chemical Property of 3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium

Chemical Property:

Appearance/Colour:Off-white solid
Vapor Pressure:0.00029mmHg at 25°C
Melting Point:60-70 °C
Boiling Point:321.8 °C at 760 mmHg
PKA:12.71±0.46(Predicted)
Flash Point:148.4 °C
Density:0.981 g/cm³
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:215.175952981
Heavy Atom Count:15
Complexity:211

Purity/Quality:

99%, ^*data from raw suppliers

3-N-Boc-aminomethylPiperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): C,Xi
Hazard Codes:C,Xi
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCC1CCC[NH2+]C1
Isomeric SMILES:CC(C)(C)OC(=O)NC[C@@H]1CCC[NH2+]C1
Uses Reagent for:Preparation of 9-substituted phenanthrene-based tylophorine analogsEnzymatic acylation Reagent for: Preparation of Tylophorine analogs Enzymatic acylation

Technology Process of 3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium

There total 9 articles about 3-({[tert-Butoxy(hydroxy)methylidene]amino}methyl)piperidin-1-ium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 220031-61-8
tert-butyl (1-benzylpiperidin-3-yl)methylcarbamate

: 142643-29-6
tert-butyl (piperidin-3-ylmethyl)carbamate

Guidance literature:: With 10% palladium hydroxide on charcoal; cyclohexene; In methanol; for 20h; Inert atmosphere; Reflux;
DOI:10.1016/j.bmc.2015.06.010

Reference yield: 89.0%

: 102297-41-6
3-<amino>methyl>pyridine

: 142643-29-6
tert-butyl (piperidin-3-ylmethyl)carbamate

Guidance literature:: With hydrogen; ruthenium; In methanol; at 60 ℃; under 75006 Torr;
DOI:10.1021/jm00049a008

Reference yield:

: 3731-52-0
3-Aminomethylpyridine

: 142643-29-6
tert-butyl (piperidin-3-ylmethyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / dioxane / 3 h / Ambient temperature

2: 89 percent / H₂ / ruthenium on alumina / methanol / 60 °C / 75006 Torr

With hydrogen; ruthenium; In 1,4-dioxane; methanol;
DOI:10.1021/jm00049a008