4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide

Base Information

• Chemical Name: 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide
• CAS No.: 783323-74-0
• Molecular Formula: C₂₁H₁₆N₈O
• Molecular Weight: 396.411
• Mol file: 783323-74-0.mol

Synonyms:4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide

Chemical Property of 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide

There total 2 articles about 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carboxylate (393129-54-9) → 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide (783323-74-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Heating;

DOI:10.1016/j.bmcl.2004.06.102

Reference yield:

3-diazo-4,5-diphenylpyrazolo<3,4-c>pyridazine (79441-97-7,1022990-31-3) → 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide (783323-74-0)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / Heating

With hydrazine hydrate; In ethanol;

DOI:10.1080/10426500500272038

Reference yield: 95.0%

benzaldehyde (100-52-7) + 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbohydrazide (783323-74-0) → 8-Methyl-3,4-diphenyl-1,2,5,6,8a,9-hexaaza-fluorene-7-carboxylic acid [1-phenyl-meth-(E)-ylidene]-hydrazide

Guidance literature:

In ethanol; for 5h; Heating;

DOI:10.1016/j.bmcl.2004.06.102

upstream raw materials:

ethyl 4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carboxylate

3-diazo-4,5-diphenylpyrazolo<3,4-c>pyridazine

Downstream raw materials:

4-methyl-9,10-diphenylpyridazino[3',4':3,4]pyrazolo[5,1-c]-1,2,4-triazine-3-carbothiosemicarbazide