3-Bromo-2,6-dimethylpyridine

Base Information

• Chemical Name: 3-Bromo-2,6-dimethylpyridine
• CAS No.: 3430-31-7
• Molecular Formula: C7H8BrN
• Molecular Weight: 186.051
• Hs Code.: 2933399090
• Mol file: 3430-31-7.mol

Synonyms:2,6-Dimethyl-3-bromopyridine;2,6-Lutidine,3-bromo- (7CI,8CI);3-Bromo-2,6-lutidine;

Chemical Property of 3-Bromo-2,6-dimethylpyridine

Chemical Property:

• Vapor Pressure: 0.615mmHg at 25°C
• Refractive Index: 1.547
• Boiling Point: 194.5 °C at 760 mmHg
• PKA: 4.32±0.10(Predicted)
• Flash Point: 71.4 °C
• PSA: 12.89000
• Density: 1.415 g/cm³
• LogP: 2.46090
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%, ^*data from raw suppliers

3-Bromo-2,6-dimethylpyridine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-36/39

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 3-Bromo-2,6-dimethylpyridine, a chemical compound, has applications in various fields. In the field of organic synthesis and medicinal chemistry, it serves as a valuable intermediate for the creation of diverse organic compounds, including pharmaceuticals and agrochemicals. Its unique chemical structure allows for the introduction of specific functional groups and structural motifs into target molecules, making it a crucial building block for the development of therapeutic agents and biologically active compounds. Its role is fundamental in advancing drug discovery and the production of pharmaceuticals that target a wide range of medical conditions. Additionally, in the field of materials science, this compound may find use as a precursor for the production of specialized materials with specific properties. The presence of the bromine atom can influence the properties of resulting materials, making it valuable in the development of advanced materials, such as polymers or coatings, with tailored characteristics for various applications. Its significance varies within these fields, but it consistently plays a pivotal role in advancing chemical synthesis, drug development, and materials innovation across diverse scientific and industrial applications.

Technology Process of 3-Bromo-2,6-dimethylpyridine

There total 4 articles about 3-Bromo-2,6-dimethylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

2,6-dimethylpyridine (108-48-5) → 3-bromo-2,6-dimethylpyridine (3430-31-7) + 3,5-dibromo-2,6-dimethylpyridine (3430-34-0)

Guidance literature:

With sulfuric acid; bromine; at 155 - 175 ℃; for 24h;

Reference yield: 57.0%

2,6-dimethylpyridine (108-48-5) → 3-bromo-2,6-dimethylpyridine (3430-31-7)

Guidance literature:

With sulfuric acid; bromine; at 150 ℃; for 18h;

DOI:10.1016/j.bioorg.2003.09.001

Reference yield:

2,5-Dimethylpyrrole (625-84-3) + Bromoform (75-25-2) → 3-bromo-2,6-dimethylpyridine (3430-31-7)

Guidance literature:

With sodium ethanolate;

upstream raw materials:

2,5-Dimethylpyrrole

Bromoform

2,6-dimethylpyridine

Downstream raw materials:

7-(2,6-Dimethyl-pyridin-3-yl)-9-methyl-1,5-dihydro-imidazo[2,1-b]quinazolin-2-one

7-(2,6-dimethylpyridin-3-yl)-1,2,3,5-tetrahydroimidazo<2,1-b>quinazoline-2(1H)-one

8-Methyl-6-[2,6-dimethylpyrid-3-yl]-2-methoxyquinoline

3‐bromo‐2,6‐dimethylpyridine‐1‐oxide

Refernces

• 1、 -. "METHOD FOR PRODUCING AMIDINE DERIVATIVES". Page/Page column 83. . Retrieved 2016/03/18.
• 2、 Zimmermann, Nicole,Meggers, Eric,Schultz, Peter G.. "A second-generation copper(II)-mediated metallo-DNA-base pair". . p. 13 - 25. Retrieved 2007/10/03.