3430-34-0

Basic information

• Product Name: 2,6-Dimethyl-3,5-dibromopyridine
• Synonyms: 2-Chloro-5-Methyl-pyriMidin-4-ylaMine;Pyridine, 3,5-dibroMo-2,6-diMethyl-
• CAS NO: 3430-34-0
• Molecular Formula: C₇H₇Br₂N
• Molecular Weight: 264.96
• Product Categories: Heterocycle-Pyridine series
• Mol File: 3430-34-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 46-57 °C
• Boiling Point: 240.2 °C at 760 mmHg
• Flash Point: 99.1 °C
• Appearance: /
• Density: 1.795 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 1.96±0.20(Predicted)
• CAS DataBase Reference: 2,6-Dimethyl-3,5-dibromopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Dimethyl-3,5-dibromopyridine(3430-34-0)
• EPA Substance Registry System: 2,6-Dimethyl-3,5-dibromopyridine(3430-34-0)

Safety Data

• Hazardous Substances Data: 3430-34-0(Hazardous Substances Data)

Usage

General Description

2,6-Dimethyl-3,5-dibromopyridine is a chemical compound that belongs to the pyridine family and contains two methyl groups and two bromine atoms. Its chemical formula is C7H6Br2N2 and it is commonly used as a building block in the synthesis of pharmaceuticals, agrochemicals, and materials for research and development purposes. 2,6-Dimethyl-3,5-dibromopyridine is known for its versatile reactivity and its ability to undergo various chemical reactions, including substitution, oxidation, and coupling reactions. Its unique structure and properties make it a valuable chemical in the field of organic synthesis and medicinal chemistry.

Upstream product

• 3430-33-9 2,6-dimethylpyridin-3-amine 
• 108-48-5 2,6-dimethylpyridine 

Downstream Products

• 65907-81-5 2,6-dimethyl-3,5-diphenylpyridine 
• 1463-03-2 2,6-dimethyl-3-phenylpyridine 

Relevant articles and documents

Synthesis method of 2, 6-dimethyl-3, 5-dibromopyridine

The invention relates to the field of organic chemistry, in particular to a synthesis method of 2, 6-dimethyl-3, 5-dibromopyridine. The method includes following steps: (1), adding 2, 6-dimethyl-3-aminopyridine and acetic anhydride into a four-neck flask, rising temperature to backflow, and allowing thin-layer chromatography tracking reaction; (2), when temperature of reaction liquid in the step (1) is lowered to below 23 DEG C, dropwise adding liquid bromine, allowing reaction at 40-55 DEG C for 2-3h after dropwise adding is completed, adding water until all solid is dissolved, dropwise adding a sodium hydroxide solution, continuing reaction for 20-40min when a lot of precipitate is generated, suction-filtering, drying, and recrystallizing to obtain 2, 6-dimethyl-3-amino-5 bromopyridine;(3), adding 2, 6-dimethyl-3-amino-5 bromopyridine into a hydrogen bromide solution, dropwise adding a saturated sodium nitrite solution at the presence of cuprous bromide in a catalysis amount, controlling temperature to -3-4 DEG C, and allowing reaction for 2-3h to obtain 2, 6-dimethyl-3, 5-dibromopyridine.The method has the advantages of being mild in reaction condition, high in yield, easy-to-get in raw material, low in cost and short in process route and having industrialization prospect.

The Bromination of Lutidines

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