S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate

Base Information

• Chemical Name: S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate
• CAS No.: 33861-71-1
• Molecular Formula: C₂₂H₂₀N₂O₃S
• Molecular Weight: 392.478
• Mol file: 33861-71-1.mol

Synonyms:S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate

Chemical Property of S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate

There total 2 articles about S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-Sulfanylpyridine (2637-34-5,73018-10-7) + Z-DL-Phe-OH (3588-57-6) → S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate (33861-71-1)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/ol101620r

Reference yield:

→ S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate (33861-71-1)

Guidance literature:

Carbodiimid, Aminosaeure, Mercaptan, S.2894;

DOI:10.1039/j39710002890

Reference yield: 59.0%

S-pyridin-2-yl 2-(((benzyloxy)carbonyl)amino)-3-phenylpropanethioate (33861-71-1) → (Z)-benzyl styrylcarbamate (1251840-96-6) + N-benzyloxycarbonylamino-2-phenyl-(E)-ethylene (88425-24-5)

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); N-ethyl-N,N-diisopropylamine; catacxium A; In 1,4-dioxane; at 105 ℃; for 18h;

DOI:10.1021/ol101620r

upstream raw materials:

2-Sulfanylpyridine

Z-DL-Phe-OH

Downstream raw materials:

(Z)-benzyl styrylcarbamate

N-benzyloxycarbonylamino-2-phenyl-(E)-ethylene