(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Base Information

Chemical Name:(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine
CAS No.:107300-18-5
Molecular Formula:C₁₈H₂₈N₂O₃
Molecular Weight:320.432
Hs Code.:

Synonyms:(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Suppliers and Price of (2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

There total 4 articles about (2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 917-54-4
methyllithium

: 107381-30-6
hydrocinnamaldehyde SAMP-hydrazone

: 79-22-1
methyl chloroformate

: 107300-18-5
(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Guidance literature:: With cerium(III) chloride; Yield given. Multistep reaction; 1.) THF, 20 deg C, 2 h, 2.) THF, -78 deg C, 2 h, 3.) THF, 20 deg C, 12 h;
DOI:10.1021/ja00241a073

Reference yield:

: 79-22-1
methyl chloroformate

: 175430-70-3
(S)-(-)-1-[1-methyl-3-phenylpropylideneamino]-2-(methoxymethyl)pyrrolidine

: 1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

: 107300-18-5
(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Guidance literature:: (S)-(-)-1-[1-methyl-3-phenylpropylideneamino]-2-(methoxymethyl)pyrrolidine; With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 ℃; for 1h; Inert atmosphere;

methyl chloroformate; In tetrahydrofuran; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.04.042

Reference yield:

: C₁₆H₂₆N₂O

: 79-22-1
methyl chloroformate

: 107300-18-5
(2S,2''R)-1-[N-methoxycarbonyl-N-(1-methyl-3-phenylpropyl)amino]-2-(methoxymethyl)pyrrolidine

Guidance literature:: In tetrahydrofuran; diethyl ether; at 20 ℃; for 12h; optical yield given as %de; Inert atmosphere;
DOI:10.1016/j.tetasy.2010.04.042