1-Aminoacridine

Base Information

• Chemical Name: 1-Aminoacridine
• CAS No.: 578-06-3
• Molecular Formula: C13H10N2
• Molecular Weight: 194.23
• NSC Number: 170666
• UNII: LB79BVP4V6
• DSSTox Substance ID: DTXSID40870623
• Nikkaji Number: J55.078G
• Wikidata: Q81986575
• ChEMBL ID: CHEMBL146525
• Mol file: 578-06-3.mol

Synonyms:9 Aminoacridine;9-Aminoacridine;Acridinamine;Aminacrine;Aminacrine Hydrochloride;Aminoacridine;Aminoacridine Hydrochloride;Aminopt;Hydrochloride, Aminacrine;Hydrochloride, Aminoacridine;Mykocert

Chemical Property of 1-Aminoacridine

Chemical Property:

• Vapor Pressure: 2.95E-07mmHg at 25°C
• Melting Point: 183°C
• Refractive Index: 1.5014 (estimate)
• Boiling Point: 419.8°C at 760 mmHg
• PKA: 5.68±0.10(Predicted)
• Flash Point: 237.2°C
• PSA: 38.91000
• Density: 1.268g/cm³
• LogP: 3.55140
• Water Solubility.: 11.65mg/L(24 oC)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 194.084398327
• Heavy Atom Count: 15
• Complexity: 229

Purity/Quality:

99% ^*data from raw suppliers

1-AMINOACRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Dyes -> Acridine Dyes
• Canonical SMILES: C1=CC=C2C(=C1)C=C3C(=N2)C=CC=C3N

Technology Process of 1-Aminoacridine

There total 9 articles about 1-Aminoacridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-aminoacridin-9(10H)-one (66073-40-3) → acridin-1-ylamine (578-06-3)

Guidance literature:

With sodium amalgam; ethanol; water; anschl. mit FeCl₃ und wss. HCl;

DOI:10.1021/ja01877a503 DOI:10.1039/jr9460000102

Reference yield:

N-phenyl-5-amino isatin → acridin-1-ylamine (578-06-3)

Guidance literature:

Reference yield:

1-Nitroacridine (30904-48-4) → acridin-1-ylamine (578-06-3)

Guidance literature:

With hydrogenchloride; water; tin(ll) chloride;

upstream raw materials:

1-aminoacridin-9(10H)-one

1-Nitroacridine

1-nitro-9-acridanone

2-acetylamino-6-anilino-benzoic acid

Downstream raw materials:

1-hydroxyacridine

N-acridin-1-yl-acetamide