8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Base Information

Chemical Name:8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide
CAS No.:86948-62-1
Molecular Formula:C₃₃H₄₆N₂O₇Se₂Si
Molecular Weight:768.743
Hs Code.:

Synonyms:8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Suppliers and Price of 8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

There total 6 articles about 8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 51694-22-5
ortho-nitrophenyl selenocyanate

: 86992-99-6
8α-t-butyldimethylsilyloxy-2,3-dihydroxy-5,7αH,6,11βH-eleman-6,12-olide

: 86948-63-2
(3S,3aS,4S,6S,7S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7-((S)-2-hydroxy-1-methyl-ethyl)-3,6-dimethyl-6-[2-(2-nitro-phenylselanyl)-ethyl]-hexahydro-benzofuran-2-one

: 86948-62-1
8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Guidance literature:: With tributylphosphine; In tetrahydrofuran; for 6h; Ambient temperature;
DOI:10.1016/S0040-4020(01)91278-5

Reference yield: 79.0%

: (2-nitrophenyl)seleno cyanate

: 86992-99-6
8α-t-butyldimethylsilyloxy-2,3-dihydroxy-5,7αH,6,11βH-eleman-6,12-olide

: 86948-63-2
(3S,3aS,4S,6S,7S,7aR)-4-(tert-Butyl-dimethyl-silanyloxy)-7-((S)-2-hydroxy-1-methyl-ethyl)-3,6-dimethyl-6-[2-(2-nitro-phenylselanyl)-ethyl]-hexahydro-benzofuran-2-one

: 86948-62-1
8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Guidance literature:: With tributylphosphine; In tetrahydrofuran; for 6h; Ambient temperature;
DOI:10.1016/S0040-4039(00)81759-1

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 86948-62-1
8α-t-butyldimethylsilyloxy-2,3-di-o-nitrophenylseleno-5,7-αH,6,11βH-eleman-6,12-olide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) H₂, 2.) imidazole / 1.) 5percent Pd-C / 1.) acetone, 2.) DMF, 30-40 deg C, 3.5 h

2: 1.) p-toluenesulphonylhydrazine, BF₃*Et₂O, 2.) LDA / 1.) benzene, 30 deg C, 3 h, 2.) THF/hexane, -78 deg C, then 0 deg C, 2 h

3: 1.) O₃, 2.) NaBH₄ / 1.) CH₂Cl₂, ethanol, -78 deg C, 15 min, 2.) -78 deg C, 45 min, then RT

4: 79 percent / n-Bu₃P / tetrahydrofuran / 6 h / Ambient temperature

With 1H-imidazole; sodium tetrahydroborate; tributylphosphine; boron trifluoride diethyl etherate; hydrogen; ozone; toluene-4-sulfonic acid hydrazide; lithium diisopropyl amide; palladium on activated charcoal; In tetrahydrofuran;
DOI:10.1016/S0040-4020(01)91278-5