5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

Base Information

Chemical Name:5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine
CAS No.:1609578-84-8
Molecular Formula:C₂₀H₁₇N₃O₂
Molecular Weight:331.374
Hs Code.:

Synonyms:5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

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Technology Process of 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

There total 2 articles about 5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 186593-43-1
5-amino-3-bromo-2-methylpyridine

: 1609581-01-2
4-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]furo[3,2-c]pyridine

: 1609578-84-8
5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; water; for 0.416667h; under 15514.9 Torr; Microwave irradiation; Heating;
DOI:10.1021/acs.jmedchem.9b00351

Reference yield:

: 1609578-84-8
5-[4-(furo[3,2-c]pyridin-4-yloxy)-2-methylphenyl]-6-methylpyridin-3-amine

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium phosphate tribasic trihydrate; In 2-methyltetrahydrofuran; water; at 75 ℃; for 18h;