Exalamide

Base Information

Chemical Name:Exalamide
CAS No.:53370-90-4
Molecular Formula:C13H19 N O2
Molecular Weight:221.299
Hs Code.:2924299090
European Community (EC) Number:258-504-3
NSC Number:758449
UNII:7JEC65JCG2
DSSTox Substance ID:DTXSID9045899
Nikkaji Number:J3.195J
Wikidata:Q27114461
NCI Thesaurus Code:C65607
ChEMBL ID:CHEMBL1405973
Mol file:53370-90-4.mol

Synonyms:2-hexyloxybenzamide;exalamide;ortho-hexyloxybenzamide

Suppliers and Price of Exalamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Exalamide
250mg
$ 260.00

Medical Isotopes, Inc.
Exalamide
0.5 g
$ 1760.00

Crysdot
Exalamide 98+%
50mg
$ 52.00

ChemScene
Exalamide 99.99%
10mg
$ 120.00

American Custom Chemicals Corporation
EXALAMIDE 95.00%
1G
$ 1124.55

American Custom Chemicals Corporation
EXALAMIDE 95.00%
100MG
$ 704.55

AK Scientific
Exalamide
25mg
$ 117.00

AHH
Exalamide 98%
1g
$ 280.00

Total 28 raw suppliers

Chemical Property of Exalamide

Chemical Property:

Appearance/Colour:white powder
Vapor Pressure:2.83E-05mmHg at 25°C
Melting Point:72-74°C
Refractive Index:1.5175 (estimate)
Boiling Point:356.9 °C at 760 mmHg
PKA:15.62±0.50(Predicted)
Flash Point:149.1 °C
PSA：52.32000
Density:1.03 g/cm³
LogP:3.44490
Storage Temp.:Refrigerator
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:221.141578849
Heavy Atom Count:16
Complexity:206

Purity/Quality:

99% ^*data from raw suppliers

Exalamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCOC1=CC=CC=C1C(=O)N
Uses Exalamide is used as an antifungal (topical). Exalamide is a derivative of salicylamide.
Therapeutic Function Antifungal

Technology Process of Exalamide

There total 3 articles about Exalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 15226-74-1,61091-28-9,61117-58-6
dicobalt octacarbonyl

: 105474-59-7
1-bromo-2-(hexyloxy)benzene

: 53370-90-4
2-hexyloxybenzamide

Guidance literature:: With 1H-imidazole; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; ammonium chloride; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 90 ℃; for 3h; Sealed tube;
DOI:10.1016/j.tetlet.2015.06.054

Reference yield: 56.0%

: 201230-82-2
carbon monoxide

: 105474-59-7
1-bromo-2-(hexyloxy)benzene

: 53370-90-4
2-hexyloxybenzamide

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; (2R)-1-[(1R)-1-[bis(1,1-dimethylethyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene; ammonium carbamate; sodium hydrogencarbonate; In 1,4-dioxane; at 100 ℃; for 20h; Inert atmosphere;
DOI:10.1021/ol201808y