(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Base Information

Chemical Name:(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside
CAS No.:287400-86-6
Molecular Formula:C₅₄H₈₂O₁₃Si
Molecular Weight:967.323
Hs Code.:

(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Synonyms:(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Suppliers and Price of (4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

There total 17 articles about (4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 287400-85-5
2,2-dimethyl-propionic acid 4-[6-[[4,5-bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-(4-methoxy-benzyloxy)-methyl]-4-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-3-methyl-tetrahydro-pyran-2-yl]-butyl ester

: 287400-86-6
(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 15h;
DOI:10.1021/jo0002801

Reference yield:

: 287400-80-0
[2S,3R]-2-methyl-3-[(triethylsilyl)oxy]-6-trimethylacetoxy-heptanal

: 287400-86-6
(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: Et₃N; chlorodicyclohexylborane / CH₂Cl₂ / 3 h / cooling

1.2: CH₂Cl₂ / 2 h / -40 °C

1.3: H₂O₂ / methanol / 1 h / 0 °C

2.1: 15 g / Ph₃PHBr / tetrahydrofuran / 7 h / 0 °C

3.1: 85 percent / KHMDS / tetrahydrofuran; toluene / 0.5 h

4.1: 24.5 g / TBAF / tetrahydrofuran / 15 h

With dicyclohexylboron chloride; tetrabutyl ammonium fluoride; triphenylphosphine hydrobromide; potassium hexamethylsilazane; triethylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/ja030317+

Reference yield:

: 287400-71-9
(S)-1-[(2R,3R,4R,5S,6R)-4,5-Bis-(4-methoxy-benzyloxy)-3-methyl-6-triisopropylsilanyloxymethyl-tetrahydro-pyran-2-yl]-1-(4-methoxy-benzyloxy)-propan-2-one

: 287400-86-6
(4R,6R,7S,11R)methyl 2,6-anhydro-5,9,11,13,14,15-hexadeoxy-10-O-[(1,1-dimethylethyl)dimethylsilyl]-3,4,7-tris-O-[(4-methoxyphenyl)methyl]-5,11-dimethyl-α-D-xylo-D-threo-L-gulo-8-hexadeculo-8,12-pyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: Et₃N; chlorodicyclohexylborane / CH₂Cl₂ / 3 h / cooling

1.2: CH₂Cl₂ / 2 h / -40 °C

1.3: H₂O₂ / methanol / 1 h / 0 °C

2.1: 15 g / Ph₃PHBr / tetrahydrofuran / 7 h / 0 °C

3.1: 85 percent / KHMDS / tetrahydrofuran; toluene / 0.5 h

4.1: 24.5 g / TBAF / tetrahydrofuran / 15 h

With dicyclohexylboron chloride; tetrabutyl ammonium fluoride; triphenylphosphine hydrobromide; potassium hexamethylsilazane; triethylamine; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/ja030317+