9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine

Base Information

• Chemical Name: 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine
• CAS No.: 930294-41-0
• Molecular Formula: C₂₅H₃₅N₇O₅
• Molecular Weight: 513.597
• Mol file: 930294-41-0.mol

Synonyms:9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine

Chemical Property of 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine

There total 1 articles about 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-aminoazetidine-1-carboxylic acid tert-butyl ester (193269-78-2) + 4-[6-amino-8-methoxy-2-(2-methoxyethoxy)purin-9-ylmethyl]benzaldehyde (927822-44-4) → 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine (930294-41-0)

Guidance literature:

3-aminoazetidine-1-carboxylic acid tert-butyl ester; 4-[6-amino-8-methoxy-2-(2-methoxyethoxy)purin-9-ylmethyl]benzaldehyde; With acetic acid; In chloroform; for 0.5h;

With sodium tris(acetoxy)borohydride; In chloroform; for 3h;

With water; sodium hydrogencarbonate; In chloroform;

Reference yield: 87.0%

tert-butyl 2-(3-oxopropoxy)acetate (930294-39-6) + 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine (930294-41-0) → 9-[4-(1-tert-butoxycarbonylazetidin-3-yl)(3-tert-butoxycarbonylmethoxypropyl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine (930294-42-1)

Guidance literature:

tert-butyl 2-(3-oxopropoxy)acetate; 9-[4-(1-tert-Butoxycarbonylazetidin-3-yl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine; In chloroform; for 0.333333h;

With sodium tris(acetoxy)borohydride; In chloroform; for 13h;

With water; sodium hydrogencarbonate; In chloroform;

upstream raw materials:

3-aminoazetidine-1-carboxylic acid tert-butyl ester

4-[6-amino-8-methoxy-2-(2-methoxyethoxy)purin-9-ylmethyl]benzaldehyde

Downstream raw materials:

9-[4-(1-tert-butoxycarbonylazetidin-3-yl)(3-tert-butoxycarbonylmethoxypropyl)aminomethylbenzyl]-8-methoxy-2-(2-methoxyethoxy)adenine