[(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate

Base Information

• Chemical Name: [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate
• CAS No.: 796073-61-5
• Molecular Formula: C₁₈H₂₂O₆S₂
• Molecular Weight: 398.501
• Mol file: 796073-61-5.mol

Synonyms:[(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate

Chemical Property of [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate

There total 2 articles about [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(R)-butane-1,3-diol (6290-03-5) + p-toluenesulfonyl chloride (98-59-9) → [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate (796073-61-5)

Guidance literature:

With pyridine; In toluene; at 0 - 20 ℃; for 2.08333h;

Reference yield:

(R)-butane-1,3-diol (6290-03-5) + p-toluenesulfonyl chloride (98-59-9) → [(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate (796073-61-5) + (R)-3-hydroxy-1-(p-toluenesulfonyloxy)butane (75351-36-9)

Guidance literature:

With dmap; trimethylamine hydrochloride; triethylamine; In toluene; at -6 - 6 ℃; for 6h; Reagent/catalyst; Overall yield = 147.5 g;

Reference yield:

[(3R)-3-(p-tolylsulfonyloxy)butyl] 4-methylbenzenesulfonate (796073-61-5) + 1-methyl-5-nitro-1,3-dihydro-2H-benzo[d]imidazol-2-one (66108-85-8) → [(1R)-1-methyl-3-(3-methyl-6-nitro-2-oxobenzimidazol-1-yl)propyl] 4-methylbenzenesulfonate

Guidance literature:

With caesium carbonate; In acetonitrile; at 60 ℃; for 2h;

upstream raw materials:

(R)-butane-1,3-diol

p-toluenesulfonyl chloride

Downstream raw materials:

R-3-O-p-toluenesulfonyl-pentanenitrile