1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol

Base Information

• Chemical Name: 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol
• CAS No.: 313946-60-0
• Molecular Formula: C₃₁H₂₈Cl₂O₃
• Molecular Weight: 519.468
• Mol file: 313946-60-0.mol

Synonyms:1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol

Chemical Property of 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol

There total 2 articles about 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-tert-butylphenyllithium (52866-85-0) + 1,5-dichloro-10-hydroxy-10'-(4-methoxyphenyl)(10H)anthracene-9-one (313946-59-7) → 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol (313946-60-0)

Guidance literature:

In tetrahydrofuran; hexane; at 20 ℃;

DOI:10.3390/50300620

Reference yield:

4-methoxyphenyl magnesium bromide (13139-86-1) → 1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol (313946-60-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 48 percent / tetrahydrofuran / 12 h / 20 °C

2: 85 percent / hexane; tetrahydrofuran / 20 °C

In tetrahydrofuran; hexane;

DOI:10.3390/50300620

Reference yield: 73.0%

1,5-dichloro-9,10-dihydroanthracene-9-(4-(1,1,-dimethylethyl)phenyl)-10-(4-methoxyphenyl)9,10-diol (313946-60-0) → 9-(4-tert-butyl-phenyl)-1,5-dichloro-10-(4-methoxy-phenyl)-anthracene (313946-61-1)

Guidance literature:

With sodium hypophosphite; acetic acid; potassium iodide; for 1h; Heating;

DOI:10.3390/50300620

upstream raw materials:

4-tert-butylphenyllithium

1,5-dichloro-10-hydroxy-10'-(4-methoxyphenyl)(10H)anthracene-9-one

4-methoxyphenyl magnesium bromide

Downstream raw materials:

9-(4-tert-butyl-phenyl)-1,5-dichloro-10-(4-methoxy-phenyl)-anthracene