N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid

Base Information

• Chemical Name: N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid
• CAS No.: 1188391-80-1
• Molecular Formula: C₁₄H₁₇NO₄
• Molecular Weight: 263.293
• Mol file: 1188391-80-1.mol

Synonyms:N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid

Chemical Property of N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid

There total 2 articles about N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

phenylmethyl 5-oxo-1,3-oxazolidine-3-carboxylate (55740-06-2) + allyl-trimethyl-silane (762-72-1) → N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid (1188391-80-1)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane;

DOI:10.1055/s-0028-1088072

Reference yield:

C15H19NO4 → N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid (1188391-80-1)

Guidance literature:

C₁₅H₁₉NO₄; With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 20 ℃; for 2h;

With hydrogenchloride; In water; at 0 ℃; pH=2 - 3;

DOI:10.1016/j.tet.2010.10.085

Reference yield:

N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid (1188391-80-1) → C13H15NO5 (1262387-38-1)

Guidance literature:

N-benzyloxycarbonyl-2-aminobut-3-enylethanoic acid; With ozone; In dichloromethane; at -78 ℃; for 1h;

With dimethylsulfide; In dichloromethane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2010.10.085

upstream raw materials:

phenylmethyl 5-oxo-1,3-oxazolidine-3-carboxylate

allyl-trimethyl-silane

Downstream raw materials:

C₁₃H₁₅NO₅