4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride

Base Information

• Chemical Name: 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride
• CAS No.: 188247-27-0
• Molecular Formula: C₁₀H₁₄N₂O*ClH
• Molecular Weight: 214.695
• Mol file: 188247-27-0.mol

Synonyms:4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride

Chemical Property of 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride

There total 2 articles about 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

4-cyano-N-methylaniline (4714-62-9) → 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride (188247-27-0)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield: 74.0%

ethanol (64-17-5) + 4-cyano-N-methylaniline (4714-62-9) → 4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride (188247-27-0)

Guidance literature:

With hydrogenchloride;

Reference yield: 32.0%

4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride (188247-27-0) + 2-amino-4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>aniline (23491-49-8) → 4-N-methyl-1-{5'-[5''-(4'''-methylpiperazin-1'''-yl)-1H-benzimidazol-2''-yl]-3H-benzimidazol-2'-yl}benzene (188247-12-3)

Guidance literature:

4-N-methylaminobenzenecarboximidic acid, ethyl ester monohydrochloride; 2-amino-4-<5'-(4''-methylpiperazin-1''-yl)benzimidazol-2'-yl>aniline; With acetic acid; In ethanol; Heating / reflux;

With ammonia; In ethanol; water;

upstream raw materials:

4-cyano-N-methylaniline

ethanol

Downstream raw materials:

4-N-methyl-1-{5'-[5''-(4'''-methylpiperazin-1'''-yl)-1H-benzimidazol-2''-yl]-3H-benzimidazol-2'-yl}benzene

Refernces

• 1、 -. "Radioprotectors". . . Retrieved 2008/06/13.