N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

Base Information

Chemical Name:N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide
CAS No.:913570-03-3
Molecular Formula:C₂₃H₂₆ClN₃O₃
Molecular Weight:427.931
Hs Code.:

Synonyms:N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

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Chemical Property of N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

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Technology Process of N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

There total 3 articles about N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [2-({[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]amino}carbonyl)phenyl]methyl benzoate

: 913570-03-3
N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

Guidance literature:: With ethanol; sodium ethanolate; at 20 ℃; for 1h;

Reference yield:

: 2-(trimethylsilyl)ethyl [1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]carbamate

: 913570-03-3
N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 50 °C

2: pyridine / dichloromethane / 2 h

3: ethanol; sodium ethanolate / 1 h / 20 °C

With pyridine; ethanol; tetrabutyl ammonium fluoride; sodium ethanolate; In tetrahydrofuran; dichloromethane;

Reference yield:

: 913568-03-3
1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-amine

: 913570-03-3
N-[1-({5-chloro-2-[(2-methylpropyl)oxy]phenyl}methyl)-5-methyl-1H-pyrazol-3-yl]-2-(hydroxymethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 2 h

2: ethanol; sodium ethanolate / 1 h / 20 °C

With pyridine; ethanol; sodium ethanolate; In dichloromethane;