3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

Base Information

Chemical Name:3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate
CAS No.:1123661-81-3
Molecular Formula:C₂HF₃O₂*C₂₅H₃₉N₃O₅
Molecular Weight:575.626
Hs Code.:

Synonyms:3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

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Chemical Property of 3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

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Technology Process of 3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

There total 1 articles about 3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133481-13-7
lithium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate

: 1123661-31-3
2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

: 76-05-1
trifluoroacetic acid

: 1123661-81-3
3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(2-ethylbutyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

Guidance literature:: 2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate; trifluoroacetic acid; In dichloromethane; for 2h;

lithium (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; for 2h;

trifluoroacetic acid; With water; acetic acid; more than 3 stages;