2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

Base Information

Chemical Name:2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate
CAS No.:1123661-31-3
Molecular Formula:C₂HF₃O₂*C₂₇H₄₃N₃O₄
Molecular Weight:587.68
Hs Code.:

Synonyms:2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

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Chemical Property of 2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

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Technology Process of 2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

There total 1 articles about 2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1123661-30-2
2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester

: 76-05-1
trifluoroacetic acid

: 1123661-31-3
2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

Guidance literature:

Reference yield:

: 1123661-31-3
2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

: 1123661-20-0
3-endo-(8-[2-(2-ethylbutylamino)ethyl]-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; for 2h;

Reference yield:

: 1123661-31-3
2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate

: 76-05-1
trifluoroacetic acid

: 13831-31-7
Acetoxyacetyl chloride

: 1123661-83-5
3-endo-(8-(2-[(2-ethylbutyl)-(2-hydroxyacetyl)amino]-ethyl)-8-azabicyclo[3.2.1]oct-3-yl)-2-hydroxybenzamide trifluoroacetate

Guidance literature:: 2-[3-endo-(3-carbamoyl-2-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl-(2-ethylbutyl)-carbamic acid tert-butyl ester trifluoroacetate; trifluoroacetic acid; In dichloromethane; for 2h;

Acetoxyacetyl chloride; With N-ethyl-N,N-diisopropylamine; In dichloromethane; for 1h;

trifluoroacetic acid; With sodium hydroxide; water; more than 3 stages;