4,4’,6,6’-tetracarboxy-2,2’-bipyridine

Base Information

• Chemical Name: 4,4’,6,6’-tetracarboxy-2,2’-bipyridine
• CAS No.: 1127385-14-1
• Molecular Formula: C₁₄H₈N₂O₈
• Molecular Weight: 332.226
• Mol file: 1127385-14-1.mol

Synonyms:4,4’,6,6’-tetracarboxy-2,2’-bipyridine

Chemical Property of 4,4’,6,6’-tetracarboxy-2,2’-bipyridine

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,4’,6,6’-tetracarboxy-2,2’-bipyridine

There total 2 articles about 4,4’,6,6’-tetracarboxy-2,2’-bipyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

4,4',6,6'-tetramethyl-2,2'-bipyridine (4444-27-3) → 4,4’,6,6’-tetracarboxy-2,2’-bipyridine (1127385-14-1)

Guidance literature:

With potassium dichromate; sulfuric acid; water; nitric acid; at 160 ℃; for 36h;

DOI:10.1016/j.tetlet.2010.12.074

Reference yield:

2,4-lutidine (108-47-4) → 4,4’,6,6’-tetracarboxy-2,2’-bipyridine (1127385-14-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: palladium 10% on activated carbon / 72 h / 160 °C

1.2: 1.5 h / 160 °C

2.1: nitric acid / water / 36 h / 160 °C / High pressure

With palladium 10% on activated carbon; nitric acid; In water;

DOI:10.1002/chem.201403872

Reference yield: 53.0%

4,4’,6,6’-tetracarboxy-2,2’-bipyridine (1127385-14-1) + [Cu(bis[2-(diphenylphosphino)phenyl]ether)(CH3CN)2]BF4 (1254575-15-9) → [Cu(bis(2-(diphenylphosphanyl)phenyl) ether)(4,4',6,6'-tetracarboxy-2,2'-bipyridine)][BF4] (1254575-05-7)

Guidance literature:

In acetone; Cu complex and ligand stirred in acetone at room temp. for 3 h; filtered; i-PrOH added to filtrate; stored overnight; solvent removed from filtrate under reduced pressure; elem. anal.;

DOI:10.1039/c0dt00190b

upstream raw materials:

4,4',6,6'-tetramethyl-2,2'-bipyridine

2,4-lutidine

Downstream raw materials:

[Cu(bis(2-(diphenylphosphanyl)phenyl) ether)(4,4',6,6'-tetracarboxy-2,2'-bipyridine)][BF₄]

2,2'-Bipyridine-4,4'-dicarboxylic acid

[2,2]bipyridinyl