1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

Base Information

Chemical Name:1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone
CAS No.:949089-68-3
Molecular Formula:C₂₆H₂₄F₉N₅O
Molecular Weight:593.495
Hs Code.:

Synonyms:1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

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Chemical Property of 1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

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Technology Process of 1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

There total 1 articles about 1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 888738-32-7
2-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-4-trifluoromethyl-benzonitrile

: 114855-97-9
(Cyclopentylmethyl)magnesium bromide

: 949089-68-3
1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

Guidance literature:: 2-{[(3,5-bis-trifluoromethyl-benzyl)-(2-methyl-2H-tetrazol-5-yl)-amino]-methyl}-4-trifluoromethyl-benzonitrile; (Cyclopentylmethyl)magnesium bromide; In diethyl ether; toluene; at 65 ℃; for 0.75h; Microwave irradiation;

With hydrogenchloride; In diethyl ether; water; ethyl acetate; toluene; at 20 ℃; for 16h;

Reference yield: 97.0%

: 949089-68-3
1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone

: 75-16-1
methylmagnesium bromide

: 949089-70-7
2-(2-(((3,5-Bis(trifluoromethyl)benzyl)(2-methyl-2H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-1-cyclopentylpropan-2-ol

Guidance literature:: 1-(2-(((3,5-bis-trifluoromethyl-benzyl)(2-methyl-2-H-tetrazol-5-yl)amino)methyl)-4-(trifluoromethyl)phenyl)-2-cyclopentylethanone; methylmagnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; for 3.5h;

With hydrogenchloride; In tetrahydrofuran; water; ethyl acetate; for 0.166667h;