2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Base Information

Chemical Name:2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide
CAS No.:1076219-29-8
Molecular Formula:C₂₃H₂₆N₂O
Molecular Weight:346.472
Hs Code.:

Synonyms:2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Suppliers and Price of 2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

There total 4 articles about 2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1076220-87-5
2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-2-methylpropanoic acid

: 765-30-0
Cyclopropylamine

: 1076219-29-8
2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Guidance literature:: With 1-chloro-1-(dimethylamino)-2-methyl-1-propene; triethylamine; In dichloromethane;
DOI:10.1016/j.bmcl.2010.11.067

Reference yield:

: 83397-45-9
ethyl 2-methyl-2-(4-nitrophenyl)propanoate

: 1076219-29-8
2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Guidance literature:: Multi-step reaction with 5 steps

1: 10% palladium on activated carbon / ethanol

2: hydrogenchloride; tin(II) chloride dihdyrate; sodium nitrite

3: acetic acid; zinc(II) chloride / ethanol

4: methanol; potassium hydroxide

5: 1-chloro-1-(dimethylamino)-2-methyl-1-propene; triethylamine / dichloromethane

With hydrogenchloride; methanol; tin(II) chloride dihdyrate; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; 10% palladium on activated carbon; acetic acid; triethylamine; potassium hydroxide; zinc(II) chloride; sodium nitrite; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2010.11.067

Reference yield:

: 36924-81-9
ethyl 2-(4-aminophenyl)-2-methylpropanoate

: 1076219-29-8
2-[2-(3,5-dimethylphenyl)-1H-indol-5-yl]-(N-cyclopropyl)-2-methylpropanamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride; tin(II) chloride dihdyrate; sodium nitrite

2: acetic acid; zinc(II) chloride / ethanol

3: methanol; potassium hydroxide

4: 1-chloro-1-(dimethylamino)-2-methyl-1-propene; triethylamine / dichloromethane

With hydrogenchloride; methanol; tin(II) chloride dihdyrate; 1-chloro-1-(dimethylamino)-2-methyl-1-propene; acetic acid; triethylamine; potassium hydroxide; zinc(II) chloride; sodium nitrite; In ethanol; dichloromethane;
DOI:10.1016/j.bmcl.2010.11.067