1,2,3,5-Tetrahydroxybenzene

Base Information

• Chemical Name: 1,2,3,5-Tetrahydroxybenzene
• CAS No.: 634-94-6
• Molecular Formula: C6H6O4
• Molecular Weight: 142.111
• UNII: 6KQM6GV7J9
• DSSTox Substance ID: DTXSID90212812
• Nikkaji Number: J134.769A
• Wikipedia: 1,2,3,5-Tetrahydroxybenzene
• Wikidata: Q3302015
• Metabolomics Workbench ID: 171532
• Mol file: 634-94-6.mol

Synonyms:1,2,3,5-Benzenetetrol;1,2,3,5-tetrahydroxybenzene;634-94-6;benzene-1,2,3,5-tetrol;6KQM6GV7J9;5-hydroxypyrogallol;UNII-6KQM6GV7J9;N-Benzylglycineethylester;HYDROXYPHLOROGLUCINOL;C03743;SCHEMBL67497;CHEBI:16746;DTXSID90212812;AKOS006312269;A8823;Q3302015

Chemical Property of 1,2,3,5-Tetrahydroxybenzene

Chemical Property:

• PSA: 80.92000
• LogP: 0.50900
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 142.02660867
• Heavy Atom Count: 10
• Complexity: 104

Purity/Quality:

99% ^*data from raw suppliers

1,2,3,5-TETRAHYDROXYBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C=C(C(=C1O)O)O)O

Technology Process of 1,2,3,5-Tetrahydroxybenzene

There total 16 articles about 1,2,3,5-Tetrahydroxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

3,4,5-trimethoxyphenol (642-71-7) → 1,2,3,5-tetrahydroxybenzene (634-94-6)

Guidance literature:

With boron tribromide; In dichloromethane; at -80 ℃; for 1h;

DOI:10.1002/chem.200601053

Reference yield: 20.0%

acide 2,4,6-trihydroxybenzoique (83-30-7) → 1,2,3,5-tetrahydroxybenzene (634-94-6) + 2,6-dihydroxy-p-benzoquinone (35069-70-6)

Guidance literature:

With air; methylene blue; In methanol; for 10h; Product distribution; Mechanism; Irradiation;

Reference yield:

2,4,6-tri(phenylmethyloxy)phenol (22132-85-0) → 1,2,3,5-tetrahydroxybenzene (634-94-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

upstream raw materials:

2,4,6-trihydroxyacetophenone

1,2,3,5-tetramethoxybenzene

1,2,3,5-tetraacetoxy-benzene

2,6-diamino-1,4-dihydroxybenzene

Downstream raw materials:

3,5-dihydroxyphenol

1,2,3,5-tetraacetoxy-benzene

1,2,3,5-tetrakis-methanesulfonyloxy-benzene

2,6-diacetyl-1,2,3,5-benzenetetrol