(+/-)-humulone

Base Information

• Chemical Name: (+/-)-humulone
• CAS No.: 125137-35-1
• Molecular Formula: C₂₁H₃₀O₅
• Molecular Weight: 362.466
• Mol file: 125137-35-1.mol

Synonyms:(+/-)-humulone

Chemical Property of (+/-)-humulone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-humulone

There total 8 articles about (+/-)-humulone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

deoxyhumulone (4374-93-0) → (+/-)-humulone (125137-35-1)

Guidance literature:

deoxyhumulone; With lead(IV) tetraacetate; palladium 10% on activated carbon; In methanol; for 4h; Inert atmosphere; Sealed tube;

With sulfuric acid; In methanol;

Reference yield:

(6S)-3,5,6-trihydroxy-2-(3-methylbutanoyl)-4,6-bis(3-methylbut-2-en-1-yl)cyclohexa-2,4-dien-1-one → (+/-)-humulone (125137-35-1)

Guidance literature:

at 125 - 145 ℃; Inert atmosphere; Sealed tube;

Reference yield:

1,2,3,5-tetrahydroxybenzene (634-94-6) → (+/-)-humulone (125137-35-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 38 percent / AlCl₃ / nitrobenzene / 72 h / Ambient temperature

2: 1.) NaH / 1.) DMSO, 2.) DMSO, 2 h, room t.

With aluminium trichloride; sodium hydride; In nitrobenzene;

DOI:10.1246/bcsj.62.3034

upstream raw materials:

phloroisovalerophenone

2,3,4,6-tetrahydroxyisovalerophenone

prenyl bromide

1,2,3,5-tetrahydroxybenzene

Downstream raw materials:

humulone