Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide

Base Information

• Chemical Name: Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide
• CAS No.: 171253-89-7
• Molecular Formula: C₂₄H₃₄N₂O₃
• Molecular Weight: 398.546
• Mol file: 171253-89-7.mol

Synonyms:Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide

Chemical Property of Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide

There total 2 articles about Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

n-octanoic acid chloride (111-64-8) + 1-(γ-aminopropyl)-3-benzyloxy-2-methyl-4-pyridinone (171253-88-6) → Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide (171253-89-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1080/00397919508015476

Reference yield:

Maltol (118-71-8) → Octanoic acid [3-(3-benzyloxy-2-methyl-4-oxo-4H-pyridin-1-yl)-propyl]-amide (171253-89-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent

2: ethanol; H₂O / 168 h / Ambient temperature

3: 93 percent / Et₃N / tetrahydrofuran / 24 h / Ambient temperature

With triethylamine; In tetrahydrofuran; ethanol; water;

DOI:10.1080/00397919508015476

upstream raw materials:

n-octanoic acid chloride

1-(γ-aminopropyl)-3-benzyloxy-2-methyl-4-pyridinone

Maltol