6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Base Information

Chemical Name:6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol
CAS No.:95250-17-2
Molecular Formula:C₁₉H₁₈Cl₃NO₄
Molecular Weight:430.715
Hs Code.:

Synonyms:6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Suppliers and Price of 6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

There total 6 articles about 6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.34%

: 95250-17-2
6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Guidance literature:

Reference yield: 80.0%

: 95250-07-0
ethyl 6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofurancarboxylate

: 95250-17-2
6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 21h;
DOI:10.1021/jm50001a009

Reference yield:

: 90246-55-2
6,7-Dichloro-2,3-dihydro-5-(p-hydroxybenzoyl)-benzofuran-2-carboxylic acid

: 95250-17-2
6,7-dichloro-2,3-dihydro-5-<3-<(chloroacetamido)methyl>-4-hydroxybenzyl>-2-benzofuranmethanol

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / conc. H₂SO₄ / 24 h / Ambient temperature

2: 66 percent / trifluoroacetic acid, NaBH₄ / CH₂Cl₂ / Ambient temperature

3: 1.) conc. H₂SO₄, 2.) conc. H₂SO₄ / 1.) acetic acid, RT, overnight, 2.) RT, overnight

4: 80 percent / NaBH₄ / ethanol / 21 h

With sodium tetrahydroborate; sulfuric acid; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1021/jm50001a009