anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate

Base Information

• Chemical Name: anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate
• CAS No.: 1416913-25-1
• Molecular Formula: C₂₃H₁₅ClO₃
• Molecular Weight: 374.823
• Mol file: 1416913-25-1.mol

Synonyms:anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate

Chemical Property of anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate

There total 1 articles about anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

9-bromoethylanthracene (2417-77-8) + 4-chlorophenylglyoxylic acid (7099-88-9) → anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate (1416913-25-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 3h;

DOI:10.1021/acs.orglett.5b03093

Reference yield: 89.0%

3-methylcyclohexen-2-one (1193-18-6) + anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate (1416913-25-1) → anthracen-9-ylmethyl (R)-2-(4-chlorophenyl)-2-hydroxy-3-(3-oxocyclohex-1-en-1-yl)propanoate (1416913-16-0)

Guidance literature:

With 1-(3,5-bis(trifluoromethyl)phenyl)-3-((1R,2R)-2-amino-1,2-diphenylethyl)thiourea; benzoic acid; In toluene; at 4 ℃; for 48h; enantioselective reaction;

DOI:10.1021/ol303312p

Reference yield: 76.0%

anthracene-9-ylmethyl 2-oxo-2-(4-chlorophenyl)acetate (1416913-25-1) + ethyl cyanoformate (623-49-4) → anthracene-9-ylmethy (S)-2-cyano-2-((ethoxycarbonyl)oxy)-2-(4-chlorophenyl)pacetate

Guidance literature:

With methanol; 3-((3,5-dinitrophenyl)amino)-4-(((1R,2R)-2-(diisopentylamino)-1,2-diphenylethyl)amino)cyclobut-3-ene-1,2-dione; In chloroform; at 20 ℃; for 12h; enantioselective reaction; Catalytic behavior;

DOI:10.1021/acs.orglett.5b03093

upstream raw materials:

9-bromoethylanthracene

4-chlorophenylglyoxylic acid

Downstream raw materials:

anthracen-9-ylmethyl (R)-2-(4-chlorophenyl)-2-hydroxy-3-(3-oxocyclohex-1-en-1-yl)propanoate