2,5-dimethylfuran-3,4-dicarboxylic Acid

Base Information

• Chemical Name: 2,5-dimethylfuran-3,4-dicarboxylic Acid
• CAS No.: 14597-13-8
• Molecular Formula: C₈H₈O₅
• Molecular Weight: 184.149
• DSSTox Substance ID: DTXSID801278274
• Nikkaji Number: J697.124E
• ChEMBL ID: CHEMBL1402092
• Mol file: 14597-13-8.mol

Synonyms:2,5-dimethylfuran-3,4-dicarboxylic Acid;14597-13-8;2,5-Dimethylfuran-3,4-dicarboxylicacid;MLS000778773;SCHEMBL2805600;CHEMBL1402092;DTXSID801278274;HMS2752G05;STL356740;AKOS003243858;2,5-dimethyl-3,4-furandicarboxylic acid;SMR000415552;2,5-Dimethyl-furan-3,4-dicarboxylic acid;DIMETHYLFURAN-3,4-DICARBOXYLIC ACID;A927872

Chemical Property of 2,5-dimethylfuran-3,4-dicarboxylic Acid

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 2
• Exact Mass: 184.03717335
• Heavy Atom Count: 13
• Complexity: 213

Purity/Quality:

97% ^*data from raw suppliers

2,5-Dimethylfuran-3,4-dicarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(C(=C(O1)C)C(=O)O)C(=O)O

Technology Process of 2,5-dimethylfuran-3,4-dicarboxylic Acid

There total 7 articles about 2,5-dimethylfuran-3,4-dicarboxylic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Diethyl 2,3-diacetylsuccinate (2049-86-7) → 2,5-dimethylfuran-3,4-dicarboxylic acid (14597-13-8)

Guidance literature:

With hydrogenchloride; In water; for 1h; Heating; Microwave irradiation;

DOI:10.1002/jhet.92

Reference yield: 50.0%

Diethyl 2,3-diacetylsuccinate (2049-86-7) → ethyl 2,5-dimethyl-3-furoate (29113-63-1) + 2,5-dimethylfuran-3,4-dicarboxylic acid (14597-13-8)

Guidance literature:

With hydrogenchloride; In water; for 14h; Reflux;

DOI:10.1002/jhet.92

Reference yield:

dimethyl 2,5-dimethylfuran-3,4-dicarboxylate (14597-14-9) → 2,5-dimethylfuran-3,4-dicarboxylic acid (14597-13-8)

Guidance literature:

With potassium carbonate;

upstream raw materials:

dimethyl 2,5-dimethylfuran-3,4-dicarboxylate

2,5-dimethyl-3,4-furandicarboxylic acid monoethyl ester

3,4-dicarboethoxy-2,5-dimethylfuran

Diethyl 2,3-diacetylsuccinate

Downstream raw materials:

2,5-dimethylfuran

methylammonium carbonate

2,5-Dimethyl-3,4-bis-(2,4,6-trimethyl-benzoyl)-furan

3,4-Bis-(2,4-dimethyl-benzoyl)-2,5-dimethyl-furan