toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Base Information

Chemical Name:toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester
CAS No.:944249-87-0
Molecular Formula:C₂₃H₂₁IO₇S
Molecular Weight:568.386
Hs Code.:

Synonyms:toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Suppliers and Price of toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

There total 5 articles about toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 944249-86-9
toluene-4-sulfonic acid 4-[(2S,3R)-3-hydroxymethyloxyranyl]phenyl ester

: 60032-63-5
4-hydroxy-3-iodo-benzaldehyde

: 944249-87-0
toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Guidance literature:: With sodium hydroxide; at 70 ℃; for 2.5h;
DOI:10.1039/b704211f

Reference yield:

: 944249-84-7
(2E)-3-[4-(toluene-4-sulfonyloxy)phenyl]-2-propenoic acid ethyl ester

: 944249-87-0
toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / DIBAL-H / tetrahydrofuran; hexane / 2 h / 0 °C

2: (-)-diisopropyl tartrate; t-BuOOH; 4 Angstroem molecular sieves / Ti(OPr-i)4 / CH₂Cl₂; 2,2,4-trimethyl-pentane / 2 h / -25 °C

3: 64 percent / aq. NaOH / 2.5 h / 70 °C

With tert.-butylhydroperoxide; sodium hydroxide; (-)-diisopropyl tartrate; 4 A molecular sieve; diisobutylaluminium hydride; titanium(IV) isopropylate; In tetrahydrofuran; 2,2,4-trimethylpentane; hexane; dichloromethane; 2: Sharpless asymmetric epoxidation;
DOI:10.1039/b704211f

Reference yield:

: 944249-85-8
toluene-4-sulfonic acid 4-[(1E)-3-hydroxy-1-propenyl]phenyl ester

: 944249-87-0
toluene-4-sulfonic acid 4-[(1S,2R)-1-(4-formyl-2,3-dihydroxy-2-iodophenoxy)propyl]phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: (-)-diisopropyl tartrate; t-BuOOH; 4 Angstroem molecular sieves / Ti(OPr-i)4 / CH₂Cl₂; 2,2,4-trimethyl-pentane / 2 h / -25 °C

2: 64 percent / aq. NaOH / 2.5 h / 70 °C

With tert.-butylhydroperoxide; sodium hydroxide; (-)-diisopropyl tartrate; 4 A molecular sieve; titanium(IV) isopropylate; In 2,2,4-trimethylpentane; dichloromethane; 1: Sharpless asymmetric epoxidation;
DOI:10.1039/b704211f