3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose

Base Information

• Chemical Name: 3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose
• CAS No.: 106734-69-4
• Molecular Formula: C₃₅H₃₆O₆
• Molecular Weight: 552.667
• Mol file: 106734-69-4.mol

Synonyms:3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose

Chemical Property of 3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose

There total 7 articles about 3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-α-D-galactofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

trityl chloride (76-83-5) + 1,2-O-isopropylidene-3-O-benzyl-α-D-glucofuranose (42926-89-6) → 3-O-Benzyl-1,2-O-isopropyliden-6-O-triphenylmethyl-α-D-glucofuranose (35777-80-1,37073-70-4,106734-68-3,106734-69-4)

Guidance literature:

With pyridine; for 12h; Inert atmosphere;

DOI:10.1039/c3ra43827a

Reference yield:

1,2:5,6-diacetone-D-glucose (582-52-5) → 3-O-Benzyl-1,2-O-isopropyliden-6-O-triphenylmethyl-α-D-glucofuranose (35777-80-1,37073-70-4,106734-68-3,106734-69-4)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide; tetrabutylammomium bromide / dichloromethane; water / 3 h / 20 °C / Inert atmosphere

2: acetic acid / water / 8 h / 20 °C / Inert atmosphere

3: pyridine / 12 h / Inert atmosphere

With pyridine; tetrabutylammomium bromide; acetic acid; sodium hydroxide; In dichloromethane; water;

DOI:10.1039/c3ra43827a

Reference yield:

3-O-benzyl-1,2;5,6-di-O-isopropylidene-α-D-glucofuranoside (101475-83-6) → 3-O-Benzyl-1,2-O-isopropyliden-6-O-triphenylmethyl-α-D-glucofuranose (35777-80-1,37073-70-4,106734-68-3,106734-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / water / 8 h / 20 °C / Inert atmosphere

2: pyridine / 12 h / Inert atmosphere

With pyridine; acetic acid; In water;

DOI:10.1039/c3ra43827a

upstream raw materials:

1,2:5,6-diacetone-D-glucose

3-O-benzyl-1,2;5,6-di-O-isopropylidene-α-D-glucofuranoside

trityl chloride

1,2-O-isopropylidene-3-O-benzyl-α-D-glucofuranose

Downstream raw materials:

3-O-benzyl-6-deoxy-1,2-O-isopropylidene-5,7-di-O-methyl-α-D-galacto-hept-6-enofuranose

3-O-benzyl-1,2-O-isopropylidene-5-O-methyl-α-D-galactofuranose

3-O-benzyl-1,2-O-isopropylidene-5-O-methyl-6-O-trityl-α-D-galactofuranose

3-O-benzyl-1,2-O-isopropylidene-6-O-(triphenylmethyl)-β-L-arabino-hexofuranos-5-ulose