SKF 83822 hydrobromide

Base Information

Chemical Name:SKF 83822 hydrobromide
CAS No.:74115-10-9
Molecular Formula:BrH*C₂₀H₂₂ClNO₂
Molecular Weight:424.765
Hs Code.:
European Community (EC) Number:804-137-4
UNII:2377D7H0WG
ChEMBL ID:CHEMBL556024
DSSTox Substance ID:DTXSID8042634
Metabolomics Workbench ID:63086
Wikidata:Q27132959

Synonyms:SKF 83822 hydrobromide;74115-10-9;SKF-83822 hydrobromide;SKF83822 hydrobromide;6-CHLORO-2,3,4,5-TETRAHYDRO-1-(3-METHYLPHENYL)-3-(2-PROPENYL)-1H-3-BENZAZEPINE-7,8-DIOL HYDROBROMIDE;UNII-2377D7H0WG;2377D7H0WG;SKF83822 (hydrobromide);CHEBI:64002;1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propen-1-yl)-, hydrobromide (1:1);1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propenyl)-, hydrobromide;9-chloro-5-(3-methylphenyl)-3-prop-2-enyl-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol;hydrobromide;N-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-3-benzazepine-7,8-diol hydrobromide;3-allyl-6-chloro-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide;3-allyl-6-chloro-7,8-dihydroxy-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide;6-chloro-1-(3-methylphenyl)-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide;6-Chloro-2,3,4,5-tetrahydro-1-(3-methylphenyl)-3-(2-propenyl)-1H-3-benzazepine-7,8-diolhydrobromide;6-chloro-7,8-dihydroxy-1-(3-methylphenyl)-3-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-3-benzazepinium bromide;CHEMBL556024;DTXSID8042634;SCHEMBL16241874;ZCA11510;AKOS024456930;NCGC00092302-01;HY-103411;CS-0027842;Q27132959;1-(3-methylphenyl)-3-prop-2-en-1-yl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol hydrobromide;6-Chloro-2,3,4,5-tetrahydro-1-(3-me thylphenyl)-3-(2-propenyl)-1H-3-benzazepine-7,8-di ol hydrobromide

Suppliers and Price of SKF 83822 hydrobromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SKF83822 hydrobromide
10mg
$ 190.00

Sigma-Aldrich
SKF83822 hydrobromide
5mg
$ 109.00

Sigma-Aldrich
SKF83822 hydrobromide
25mg
$ 436.00

ApexBio Technology
SKF83822 hydrobromide
50mg
$ 1290.00

ApexBio Technology
SKF83822 hydrobromide
10mg
$ 308.00

Total 2 raw suppliers

Chemical Property of SKF 83822 hydrobromide

Chemical Property:

Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:423.06007
Heavy Atom Count:25
Complexity:432

Purity/Quality:

≥98% by HPLC ^*data from raw suppliers

SKF83822 hydrobromide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)CC=C.Br
Uses SKF 83822 Hydrobromide is a potent agonist of peripheral dopamine receptors.

Technology Process of SKF 83822 hydrobromide

There total 6 articles about SKF 83822 hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 765218-10-8
3-allyl-6-chloro-7,8-dimethoxy-1-(3-methylphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine

: 74115-10-9
SKF₈₃₈₂₂ hydrobromide

Guidance literature:: With boron tribromide; In dichloromethane; at 25 ℃; for 18h;
DOI:10.1021/jm00346a005

Reference yield:

: 704898-29-3,1195902-12-5,20697-03-4
3-methylstyrene oxide

: 74115-10-9
SKF₈₃₈₂₂ hydrobromide

Guidance literature:: Multi-step reaction with 4 steps

1: 18 h / 110 °C

2: H₂SO₄, CF₃COOH / 2 h / Heating

3: 66 percent / K₂CO₃ / dimethylformamide / 2 h / 120 °C

4: BBr₃ / CH₂Cl₂ / 18 h / 25 °C

With sulfuric acid; boron tribromide; potassium carbonate; trifluoroacetic acid; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00346a005

Reference yield:

: 781561-80-6
6-Chloro-7,8-dimethoxy-1-m-tolyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine

: 74115-10-9
SKF₈₃₈₂₂ hydrobromide

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / K₂CO₃ / dimethylformamide / 2 h / 120 °C

2: BBr₃ / CH₂Cl₂ / 18 h / 25 °C

With boron tribromide; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm00346a005