N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

Base Information

Chemical Name:N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide
CAS No.:1253188-20-3
Molecular Formula:C₁₇H₁₂ClF₂N₃O₂
Molecular Weight:363.751
Hs Code.:

Synonyms:N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

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Technology Process of N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

There total 1 articles about N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1253188-19-0
N-[1-({2-chloro-6-[(phenylmethyl)oxy]phenyl}methyl)-1H-pyrazol-3-yl]-2,6-difluorobenzamide

: 1253188-20-3
N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

Guidance literature:: With hydrogen; palladium 10% on activated carbon; 5% Pd(II)/C(eggshell); In ethyl acetate; at 20 ℃; under 750.075 Torr;

Reference yield:

: 17247-58-4
(Bromomethyl)cyclobutane

: 1253188-20-3
N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide

: 1253186-79-6
N-[1-({2-chloro-6-[(cyclobutylmethyl)oxy]phenyl}methyl)-1H-pyrazol-3-yl]-2,6-difluorobenzamide

Guidance literature:: N-{1-[(2-chloro-6-hydroxyphenyl)methyl]-1H-pyrazol-3-yl}-2,6-difluorobenzamide; With potassium tert-butylate; In dimethyl sulfoxide; for 0.333333h;

(Bromomethyl)cyclobutane; In dimethyl sulfoxide; at 60 ℃; for 24h;