N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide

Base Information

• Chemical Name: N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide
• CAS No.: 428817-09-8
• Molecular Formula: C₂₃H₁₈N₄O₄
• Molecular Weight: 414.42
• Mol file: 428817-09-8.mol

Synonyms:N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide

Chemical Property of N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide

There total 3 articles about N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methylantranilic acid (4389-45-1) → N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide (428817-09-8)

Guidance literature:

Multi-step reaction with 3 steps

1.1: NaNO₂; HCl

1.2: NaN₃

2.1: SOCl₂

3.1: LDA

With hydrogenchloride; thionyl chloride; lithium diisopropyl amide; sodium nitrite;

DOI:10.1016/S0040-4039(01)02279-1

Reference yield:

2-azido-3-methylbenzoic acid (156149-48-3) → N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide (428817-09-8)

Guidance literature:

Multi-step reaction with 2 steps

1: SOCl₂

2: LDA

With thionyl chloride; lithium diisopropyl amide;

DOI:10.1016/S0040-4039(01)02279-1

Reference yield:

N-(benzo[d][1,3]dioxol-5-ylmethyl)benzamide (65609-38-3) + 2-azido-3-methylbenzoic acid chloride (428817-19-0) → N-(2-azido-3-methyl-benzoyl)-N-benzo[1,3]dioxol-5-ylmethyl-benzamide (428817-09-8)

Guidance literature:

With lithium diisopropyl amide;

DOI:10.1016/S0040-4039(01)02279-1

upstream raw materials:

N-(benzo[d][1,3]dioxol-5-ylmethyl)benzamide

2-azido-3-methylbenzoic acid chloride

3-methylantranilic acid

2-azido-3-methylbenzoic acid