ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

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Chemical Name:ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate
CAS No.:1031822-18-0
Molecular Formula:C₃₂H₃₆N₄O₄
Molecular Weight:540.662
Hs Code.:

Synonyms:ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

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Chemical Property of ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

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Technology Process of ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

There total 1 articles about ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 1031822-16-8
ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

: 1031822-18-0
ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

Guidance literature:: 2-Chloro-3-nitropyridine; ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate; With N-ethyl-N,N-diisopropylamine; In ethanol; at 80 ℃; for 72h;

With hydrogen; 5%-palladium/activated carbon; In ethanol; for 3h;