ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

Base Information

Chemical Name:ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate
CAS No.:1031822-16-8
Molecular Formula:C₂₇H₃₂N₂O₄
Molecular Weight:448.562
Hs Code.:

Synonyms:ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

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Technology Process of ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

There total 1 articles about ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1031822-14-6
ethyl N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-4-nitro-L-phenylalaninate

: 1031822-16-8
ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethanol; for 24h;

Reference yield: 61.0%

: 5470-18-8,34515-82-7
2-Chloro-3-nitropyridine

: 1031822-16-8
ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

: 1031822-18-0
ethyl 4-[(3-aminopyridin-2-yl)amino]-N-[7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate

Guidance literature:: 2-Chloro-3-nitropyridine; ethyl 4-amino-N-[(4R,7S)-7-(benzyloxy)-3-oxospiro[3.5]non-1-en-1-yl]-L-phenylalaninate; With N-ethyl-N,N-diisopropylamine; In ethanol; at 80 ℃; for 72h;

With hydrogen; 5%-palladium/activated carbon; In ethanol; for 3h;