Technology Process of C22H24FNO4
There total 6 articles about C22H24FNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
C28H38FNO4Si;
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 1h;
With
sodium tetrachloroaurate (III) hydrate;
In
tetrahydrofuran;
at 50 ℃;
for 6h;
DOI:10.1055/s-0033-1340251
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: n-butyllithium / tetrahydrofuran
2.1: (S)-hydroxynitrile lyase / tert-butyl methyl ether / 4 h / 0 °C / pH 5 / Enzymatic reaction
3.1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C
4.1: diethyl ether / 2.08 h / 0 - 20 °C
4.2: -78 °C
5.1: sodium hydrogencarbonate / 1,4-dioxane; water / 20 °C
6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C
6.2: 6 h / 50 °C
With
1H-imidazole; dmap; (S)-hydroxynitrile lyase; n-butyllithium; tetrabutyl ammonium fluoride; sodium hydrogencarbonate;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; tert-butyl methyl ether; water;
4.1: |Grignard Reaction;
DOI:10.1055/s-0033-1340251
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C
2.1: diethyl ether / 2.08 h / 0 - 20 °C
2.2: -78 °C
3.1: sodium hydrogencarbonate / 1,4-dioxane; water / 20 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 1 h / 0 - 20 °C
4.2: 6 h / 50 °C
With
1H-imidazole; dmap; tetrabutyl ammonium fluoride; sodium hydrogencarbonate;
In
tetrahydrofuran; 1,4-dioxane; diethyl ether; dichloromethane; water;
2.1: |Grignard Reaction;
DOI:10.1055/s-0033-1340251
