1-Ethynyl-4-methoxybenzene

Base Information Edit

Chemical Name:1-Ethynyl-4-methoxybenzene
CAS No.:768-60-5
Molecular Formula:C9H8O
Molecular Weight:132.162
Hs Code.:29093090
European Community (EC) Number:640-179-8
NSC Number:71091
DSSTox Substance ID:DTXSID20290800
Nikkaji Number:J401.609B
Wikidata:Q69758029
ChEMBL ID:CHEMBL232552
Mol file:768-60-5.mol

Synonyms:4-Ethynylanisole;768-60-5;1-Ethynyl-4-methoxybenzene;4-Methoxyphenylacetylene;1-eth-1-ynyl-4-methoxybenzene;4'-Methoxyphenyl acetylene;Benzene, 1-ethynyl-4-methoxy-;1-ethynyl-4-methoxy-benzene;4-ethynyl anisole;p-methoxyphenylacetylene;MFCD00168815;4-methoxyphenyl acetylene;4'-Methoxyphenylacetylene;4-ethynyl-1-methoxybenzene;p-ethynylanisole;4-ethynyl-anisole;NSC71091;p-Methoxyphenylethyne;4-methoxyphenylethyne;4-methoxy-phenylacetylene;4-Ethynylanisole, 97%;4'-methoxy phenylacetylene;4-methoxy-phenyl-acetylene;1-methoxy-4-ethynylbenzene;4-methoxy-1-ethynyl benzene;1-(4-methoxyphenyl)acetylene;4-CH3O-C6H4-CCH;SCHEMBL187127;1-Ethynyl-4-methoxybenzene #;CHEMBL232552;DTXSID20290800;CHEBI:194788;BBL104009;NSC 71091;NSC-71091;STL557821;AKOS005146078;CS-W004104;PS-4187;AC-19401;BP-12812;SY013463;A9736;AM20060729;E0603;FT-0618957;EN300-83248;Q-102460;F0001-1960;Z1080385508

Suppliers and Price of 1-Ethynyl-4-methoxybenzene

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methoxyphenylacetylene
10 g
$ 180.00

TRC
4-Methoxyphenylacetylene
2.5 g
$ 80.00

TCI Chemical
4-Ethynylanisole >98.0%(GC)
25g
$ 113.00

TCI Chemical
4-Ethynylanisole >98.0%(GC)
1g
$ 14.00

TCI Chemical
4-Ethynylanisole >98.0%(GC)
5g
$ 38.00

Synthonix
4-Ethynylanisole 98%
100g
$ 340.00

Synthonix
4-Ethynylanisole 98%
10g
$ 40.00

Synthonix
4-Ethynylanisole 98%
5g
$ 20.00

Synthonix
4-Ethynylanisole 98%
25g
$ 90.00

Sigma-Aldrich
4-Ethynylanisole 97%
5g
$ 294.00

Total 104 raw suppliers

Chemical Property of 1-Ethynyl-4-methoxybenzene Edit

Chemical Property:

Appearance/Colour:pale yellow oil
Melting Point:28-29 °C(lit.)
Refractive Index:n20/D 1.563(lit.)
Boiling Point:194.8 °C at 760 mmHg
Flash Point:63.5 °C
PSA：9.23000
Density:1.01 g/cm³
LogP:1.67650
Storage Temp.:Store Cold
Sensitive.:Light Sensitive
Solubility.:Acetontrile (Slightly), Chloroform (Slightly)
Water Solubility.:Insoluble in water. Soluble in chloroform, acetone, dichloromethane, and methanol.
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:132.057514874
Heavy Atom Count:10
Complexity:134

Purity/Quality:

99% ^*data from raw suppliers

4-Methoxyphenylacetylene ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xn
Hazard Codes:Xn,F
Statements: 22
Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C#C
Uses Intermediate in the synthesis of histamine H3-receptor antagonists. Also utilized to prepare its luminescent copper complex Intermediates of Liquid Crystals 1,3-dipolar cycloaddition of acceptor-cyclopropylmethylsilanes affords functionalized cyclopentenes in good yields.1 4-Ethynylanisole was used in the synthesis of photo luminescent 1,2-dihydrophosphinines via a [4 + 2] cycloaddition. Along with an arylboronic acid and sodium azide in a copper-catalyzed, three-component synthesis of trisubstituted 1,2,4-triazoles. In a study of a gold (III)-catalyzed hydroamination of alkynes leading to N-vinylindoles3.

Technology Process of 1-Ethynyl-4-methoxybenzene

There total 106 articles about 1-Ethynyl-4-methoxybenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 3989-14-8
(4-methoxyphenylethynyl)trimethylsilane

: 768-60-5
4-methoxyphenylacetylen

Guidance literature:: With methanol; potassium carbonate; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.tet.2010.11.012