2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid

Base Information

Chemical Name:2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid
CAS No.:80813-10-1
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:2932990090
European Community (EC) Number:820-766-7
Mol file:80813-10-1.mol

Synonyms:80813-10-1;2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid;2-(4-Phenyltetrahydro-2H-pyran-4-yl)acetic acid;2-(4-phenyloxan-4-yl)acetic acid;SCHEMBL15577224;AKOS022306944;KS-8213;CS-0455959;2-(4-Phenyltetrahydro-2H-pyran-4-yl)aceticacid;EN300-1699319;Z2044806623

Suppliers and Price of 2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-(4-Phenyltetrahydro-2H-pyran-4-yl)aceticacid 97%
1g
$ 668.00

Total 5 raw suppliers

Chemical Property of 2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:238

Purity/Quality:

97% ^*data from raw suppliers

2-(4-Phenyltetrahydro-2H-pyran-4-yl)aceticacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1COCCC1(CC(=O)O)C2=CC=CC=C2

Technology Process of 2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid

There total 4 articles about 2-(4-Phenyl-tetrahydro-2H-pyran-4-yl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.5%

: 80813-09-8
cyano(4-phenyltetrahydropyran-4-yl)acetate d'ethyle

: 80813-10-1
2-(4-phenyltetrahydro-2H-pyran-4-yl)acetic acid

Guidance literature:: With potassium hydroxide; water; In ethylene glycol; for 23h; Heating;
DOI:10.1016/S0022-328X(00)89049-X

Reference yield:

: 33451-54-6
ethyl 2-cyano-2-(dihydro-2H-pyran-4(3H)-ylidene)acetate

: 80813-10-1
2-(4-phenyltetrahydro-2H-pyran-4-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96.9 percent / diethyl ether / 1.5 h / Heating

2: 83.5 percent / KOH, water / ethane-1,2-diol / 23 h / Heating

With potassium hydroxide; water; In diethyl ether; ethylene glycol;
DOI:10.1016/S0022-328X(00)89049-X

Reference yield:

: phenylmagnesium bromide

: 80813-10-1
2-(4-phenyltetrahydro-2H-pyran-4-yl)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 96.9 percent / diethyl ether / 1.5 h / Heating

2: 83.5 percent / KOH, water / ethane-1,2-diol / 23 h / Heating

With potassium hydroxide; water; In diethyl ether; ethylene glycol;
DOI:10.1016/S0022-328X(00)89049-X