Chemical Property of 1-Aminocyclopropane-1-carboxylate
Chemical Property:
- Appearance/Colour:Crystalline
- Vapor Pressure:0.0256mmHg at 25°C
- Melting Point:229-231 °C(lit.)
- Refractive Index:1.568
- Boiling Point:228.9 °C at 760 mmHg
- PKA:2.29±0.20(Predicted)
- Flash Point:92.2 °C
- PSA：63.32000
- Density:1.414 g/cm3
- LogP:0.26260
- Storage Temp.:Store at 0°C
- Solubility.:DMSO (Slightly), Water (Slightly)
- Water Solubility.:Soluble in water.
- XLogP3:-2.1
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:2
- Rotatable Bond Count:0
- Exact Mass:101.047678466
- Heavy Atom Count:7
- Complexity:101
- Purity/Quality:
-
99% *data from raw suppliers
1-Aminocyclopropane-1-carboxylic Acid *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36-37/39
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1CC1(C(=O)[O-])[NH3+]
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Description
1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate. 1-Aminocyclopropanecarboxylic acid has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.
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Uses
1-Aminocyclopropane-1-carboxylic Acid is a plant growth regulator. It is an NMDA agonist acting at the glycine site. 1-Aminocyclopropane-1-carboxylic Acid is an intermediate in the conversion of methionine to ethylene during the ripening in apples. It also plays an important role in the biosynthesis of the plant hormone ethylene.1-Aminocyclopropane-1-carboxylic Acid is shown to block convulsions and death produced by NMDA exposure, significantly reducing seizure induction and cell death of NMDA-treated hippocampal neurons. 1-Aminocyclopropane-1-carboxylic Acid is produced endogenously in the tomato and other higher plants as a product of the action of 1-aminocyclopropane-1-carboxylic acid synthase in the biosynthesis of ethylene.
