Technology Process of 2-benzyloxy-1,5,7,8-tetramethoxy-3-(2-nitroethyl)naphthalene
There total 7 articles about 2-benzyloxy-1,5,7,8-tetramethoxy-3-(2-nitroethyl)naphthalene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
methanol; dichloromethane;
for 0.25h;
Cooling with ice;
DOI:10.1021/jo200399z
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium dithionite; water / benzene / 0.08 h
2: potassium carbonate / N,N-dimethyl-formamide / 120 h
3: potassium carbonate / N,N-dimethyl-formamide / 22 h / 20 °C
4: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / Cooling with ice
5: Dess-Martin periodane / dichloromethane / 1.1 h / Cooling with ice
6: ammonium acetate / 13 h / 120 °C
7: sodium tetrahydroborate / methanol; dichloromethane / 0.25 h / Cooling with ice
With
sodium tetrahydroborate; lithium aluminium tetrahydride; sodium dithionite; ammonium acetate; water; potassium carbonate; Dess-Martin periodane;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo200399z
- Guidance literature:
-
Multi-step reaction with 6 steps
1: potassium carbonate / N,N-dimethyl-formamide / 120 h
2: potassium carbonate / N,N-dimethyl-formamide / 22 h / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / Cooling with ice
4: Dess-Martin periodane / dichloromethane / 1.1 h / Cooling with ice
5: ammonium acetate / 13 h / 120 °C
6: sodium tetrahydroborate / methanol; dichloromethane / 0.25 h / Cooling with ice
With
sodium tetrahydroborate; lithium aluminium tetrahydride; ammonium acetate; potassium carbonate; Dess-Martin periodane;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo200399z
