3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Base Information

Chemical Name:3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine
CAS No.:797040-52-9
Molecular Formula:C₂₇H₃₃N₅O₃S
Molecular Weight:507.657
Hs Code.:

Synonyms:3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Suppliers and Price of 3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

There total 9 articles about 3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-43-6,329041-72-7
4-vinylpyridine

: 797040-52-9
3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Guidance literature:: Multi-step reaction with 6 steps

1: 46.9 g / ammonium chloride / H₂O; methanol / Heating

2: 2-methyl-propan-2-ol / 12 h / 20 °C

3: 21.9 g / H₂; AcOH / PtO₂ / 96 h / 35 °C

4: PyBop; diisopropylethylamine / dimethylformamide / 0 - 20 °C

5: aq. HCl; AcOH / 1 h / 20 °C

6: aq. AcOH; H₂ / Pd/C / 40 °C

With hydrogenchloride; ammonium chloride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; acetic acid; N-ethyl-N,N-diisopropylamine; platinum(IV) oxide; palladium on activated charcoal; In methanol; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jm051272l

Reference yield:

: C₂₉H₃₅N₅O₅S

: 797040-52-9
3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; at 40 ℃;
DOI:10.1021/jm051272l

Reference yield:

: (S)-3-(3-Cyano-phenyl)-2-(naphthalene-1-sulfonylamino)-propionic acid

: 797040-52-9
3-[(S)-3-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-(naphthalene-1-sulfonylamino)-3-oxo-propyl]-benzamidine

Guidance literature:: Multi-step reaction with 5 steps

1: hydroxylamine*HCl; diisopropylethylamine / ethanol / Heating

2: AcOH / 20 °C

3: PyBop; diisopropylethylamine / dimethylformamide / 0 - 20 °C

4: aq. HCl; AcOH / 1 h / 20 °C

5: aq. AcOH; H₂ / Pd/C / 40 °C

With hydrogenchloride; hydroxylamine hydrochloride; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; hydrogen; acetic acid; N-ethyl-N,N-diisopropylamine; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm051272l