4-(2-Boc-aminoethyl)piperidine

Base Information

Chemical Name:4-(2-Boc-aminoethyl)piperidine
CAS No.:165528-81-4
Molecular Formula:C12H24N2O2
Molecular Weight:228.335
Hs Code.:2933399090
European Community (EC) Number:688-374-7
DSSTox Substance ID:DTXSID10363537
Nikkaji Number:J2.348.862K
Wikidata:Q72448089
ChEMBL ID:CHEMBL4525509
Mol file:165528-81-4.mol

Synonyms:165528-81-4;4-(2-BOC-AMINOETHYL)PIPERIDINE;4-[2-(Boc-amino)ethyl]piperidine;tert-butyl (2-(piperidin-4-yl)ethyl)carbamate;(2-Piperidin-4-yl-ethyl)-carbamic acid tert-butyl ester;tert-butyl N-(2-piperidin-4-ylethyl)carbamate;tert-butyl N-[2-(piperidin-4-yl)ethyl]carbamate;tert-butyl 2-(piperidin-4-yl)ethylcarbamate;MFCD01318373;Carbamic acid, [2-(4-piperidinyl)ethyl]-, 1,1-dimethylethyl ester;Carbamic acid, N-[2-(4-piperidinyl)ethyl]-, 1,1-dimethylethyl ester;tert-butyl (2-piperidin-4-ylethyl)carbamate;SCHEMBL346052;CHEMBL4525509;DTXSID10363537;CS-B0446;AKOS000160613;PS-4227;SB43150;AC-24270;BL000877;SY023589;tert-butyl 2-piperidin-4-ylethylcarbamate;BB 0262509;FT-0648147;4-(2-Boc-aminoethyl) piperidine, AldrichCPR;4-(2-tert-Butoxycarbonylaminoethyl)piperidine;EN300-76331;tert-butyl(2-(piperidin-4-yl)ethyl)carbamate;4-(2-tert-butoxycarbonylaminoethyl)-piperidine;N-(tert-Butoxycarbonyl)piperidine-4-ethaneamine;tert-Butyl 2-(piperidin-4-yl)(ethyl)carbamate;N-t-butoxycarbonyl 2-(piperidin-4-yl)-ethylamine;Q-102973;1,1-dimethylethyl [2-(4-piperidinyl)ethyl]carbamate;(2-Piperidin-4-ylethyl) carbamic acid tert-butyl ester;N-[2-(4-piperidinyl)ethyl]-carbamic acid tert-butyl ester

Suppliers and Price of 4-(2-Boc-aminoethyl)piperidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Boc-aminoethyl)piperidine
500mg
$ 105.00

TRC
4-(2-Boc-aminoethyl)piperidine
100mg
$ 45.00

SynChem
TERT-BUTYL 2-(PIPERIDIN-4-YL)ETHYLCARBAMATE 95%
1 g
$ 115.00

Matrix Scientific
tert-Butyl (2-(piperidin-4-yl)ethyl)carbamate 95%
500mg
$ 217.00

Matrix Scientific
tert-Butyl (2-(piperidin-4-yl)ethyl)carbamate 95%
5g
$ 1055.00

Matrix Scientific
tert-Butyl (2-(piperidin-4-yl)ethyl)carbamate 95%
1g
$ 349.00

Crysdot
4-(2-Boc-aminoethyl)piperidine 95+%
5g
$ 290.00

Chemenu
tert-butyl2-(piperidin-4-yl)ethylcarbamate 95%
5g
$ 241.00

Biosynth Carbosynth
4-(2-Boc-aminoethyl)piperidine
5 g
$ 325.00

Biosynth Carbosynth
4-(2-Boc-aminoethyl)piperidine
10 g
$ 600.00

Total 54 raw suppliers

Chemical Property of 4-(2-Boc-aminoethyl)piperidine

Chemical Property:

Vapor Pressure:0.000106mmHg at 25°C
Refractive Index:1.459
Boiling Point:337.3 °C at 760 mmHg
PKA:12.86±0.46(Predicted)
Flash Point:157.8 °C
PSA：50.36000
Density:0.971 g/cm³
LogP:2.62050
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:1.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:228.183778013
Heavy Atom Count:16
Complexity:218

Purity/Quality:

97% ^*data from raw suppliers

4-(2-Boc-aminoethyl)piperidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NCCC1CCNCC1

Technology Process of 4-(2-Boc-aminoethyl)piperidine

There total 1 articles about 4-(2-Boc-aminoethyl)piperidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-43-6,329041-72-7
4-vinylpyridine

: 165528-81-4
tert-butyl 2-(piperidin-4-yl)ethylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: 46.9 g / ammonium chloride / H₂O; methanol / Heating

2: 2-methyl-propan-2-ol / 12 h / 20 °C

3: 21.9 g / H₂; AcOH / PtO₂ / 96 h / 35 °C

With ammonium chloride; hydrogen; acetic acid; platinum(IV) oxide; In methanol; water; tert-butyl alcohol;
DOI:10.1021/jm051272l

Reference yield: 100.0%

: 1175526-48-3
3,5-dichlorobenzyl carbonochloridate

: 165528-81-4
tert-butyl 2-(piperidin-4-yl)ethylcarbamate

: 1613512-87-0
3,5-dichlorobenzyl 4-(2-((tert-butoxycarbonyl)amino)ethyl)piperidine-1-carboxylate

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 3h;
DOI:10.1016/j.bmcl.2018.05.030

Reference yield: 99.16%

: 1975-51-5
2-methyl-4-nitrobenzoic acid

: 165528-81-4
tert-butyl 2-(piperidin-4-yl)ethylcarbamate

: tert-butyl N-[2-[1-(2-methyl-4-nitro-benzoyl)-4-piperidyl]ethyl]carbamate

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; triethylamine; In N,N-dimethyl-formamide; at 25 ℃; for 3h; Inert atmosphere;