phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside

Base Information

• Chemical Name: phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside
• CAS No.: 819798-14-6
• Molecular Formula: C₃₅H₃₅ClO₆S
• Molecular Weight: 619.178
• Mol file: 819798-14-6.mol

Synonyms:phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside

Chemical Property of phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside

There total 1 articles about phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranoside (38184-12-2,120403-26-1,87470-73-3) + chloroacetyl chloride (79-04-9) → phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside (819798-14-6)

Guidance literature:

In pyridine; dichloromethane; at 0 - 20 ℃; for 2h;

Reference yield: 95.0%

phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside (819798-14-6) → 2,3,4-tri-O-benzyl-6-O-chloroacetyl-α-D-galactopyranosyl fluoride (904666-13-3)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at 0 - 40 ℃; for 3.5h;

DOI:10.1016/j.carres.2006.03.040

Reference yield: 82.0%

phenyl 2,3,4-tri-O-benzyl-6-O-chloroacetyl-1-thio-β-D-galactopyranoside (819798-14-6) → chloro-acetic acid 3,4,5-tris-benzyloxy-6-fluoro-tetrahydro-pyran-2-ylmethyl ester

Guidance literature:

With N-Bromosuccinimide; diethylamino-sulfur trifluoride; at -15 ℃; for 1h;

upstream raw materials:

phenyl 2,3,4-tri-O-benzyl-1-thio-β-D-galactopyranoside

chloroacetyl chloride

Downstream raw materials:

2,3,4-tri-O-benzyl-6-O-chloroacetyl-α-D-galactopyranosyl fluoride

2,3,4-tri-O-benzyl-α-D-galactopyranosyl fluoride

C₆₂H₇₄O₁₀

phenyl 2,3,4-tri-O-benzyl-6-O-{4-[(5-dimethylaminonaphthalene-1-sulfonylamino)methyl]-1H-1,2,3-triazol-1-yl}acetyl-1-thio-β-D-galactopyranoside