N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

Base Information

Chemical Name:N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide
CAS No.:1353023-87-6
Molecular Formula:C₂₁H₁₅ClN₂O₄
Molecular Weight:394.814
Hs Code.:

Synonyms:N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

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Chemical Property of N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

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Technology Process of N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

There total 1 articles about N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1045704-67-3
2-(4-chloro-2-aminophenyl)-5-methylfuran

: 6780-38-7
N-phthaloylglycine chloride

: 1353023-87-6
N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

Guidance literature:: In benzene; at 20 ℃; for 0.333333h;
DOI:10.1055/s-0030-1260204

Reference yield: 88.0%

: 1353023-87-6
N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

: 1353023-93-4
2-amino-N-[5-chloro-2-(5-methyl-2-furyl)phenyl]acetamide

Guidance literature:: With hydrazine hydrate; In ethanol; for 0.0833333h; Reflux;
DOI:10.1055/s-0030-1260204

Reference yield:

: 1353023-87-6
N-[5-chloro-2-(5-methyl-2-furyl)phenyl]-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)acetamide

: C₁₃H₁₅ClN₂O₃

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 0.08 h / Reflux

2: hydrogenchloride; acetic acid / water / 0.67 h / Reflux

With hydrogenchloride; hydrazine hydrate; acetic acid; In ethanol; water;
DOI:10.1055/s-0030-1260204