[6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide

Base Information

• Chemical Name: [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide
• CAS No.: 474460-07-6
• Molecular Formula: C₂₁H₂₃ClN₄OS
• Molecular Weight: 414.959
• Mol file: 474460-07-6.mol

Synonyms:[6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide

Chemical Property of [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide

Chemical Property:

Purity/Quality:

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• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide

There total 1 articles about [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-ethylcyclohexanone (5441-51-0) + (6-(4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazide (158196-99-7) → [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide (474460-07-6)

Guidance literature:

In ethanol; for 6h; Heating;

Reference yield: 98.0%

2-mercaptopropanoic acid (79-42-5) + [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide (474460-07-6) → 2-[6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-N-(8-ethyl-2-methyl-3-oxo-1-thia-4-aza-spiro[4.5]dec-4-yl)-acetamide

Guidance literature:

97; In benzene; for 48h; Heating;

Reference yield: 98.0%

mercaptoacetic acid (68-11-1) + [6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-acetic acid (4-ethyl-cyclohexylidene)-hydrazide (474460-07-6) → 2-[6-(4-chloro-phenyl)-imidazo[2,1-b]thiazol-3-yl]-N-(8-ethyl-3-oxo-1-thia-4-aza-spiro[4.5]dec-4-yl)-acetamide

Guidance literature:

In benzene; for 48h; Heating;

upstream raw materials:

4-ethylcyclohexanone

(6-(4-chlorophenyl)imidazo[2,1-b]thiazol-3-yl)acetic acid hydrazide