3-nitro-6-phenylphenanthridine

Base Information

• Chemical Name: 3-nitro-6-phenylphenanthridine
• CAS No.: 109469-92-3
• Molecular Formula: C₁₉H₁₂N₂O₂
• Molecular Weight: 300.316
• Mol file: 109469-92-3.mol

Synonyms:3-nitro-6-phenylphenanthridine

Chemical Property of 3-nitro-6-phenylphenanthridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 3-nitro-6-phenylphenanthridine

There total 10 articles about 3-nitro-6-phenylphenanthridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

2'-benzyl-4'-nitro-[1,1'-biphenyl]-2-amine → 3-nitro-6-phenylphenanthridine (109469-92-3)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; iodine; caesium carbonate; at 80 ℃; for 3h;

DOI:10.1039/d0ob00433b

Reference yield: 80.0%

2-bromo-5-nitro-benzophenone (183110-88-5) + tert-butyl N-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamate (159624-15-4) → 3-nitro-6-phenylphenanthridine (109469-92-3)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethylene glycol; at 120 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c6ra00249h

Reference yield:

2-aminophenylboronic acid (5570-18-3) + C13H10BrNO2 → 3-nitro-6-phenylphenanthridine (109469-92-3)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate / toluene; ethanol; water / 12 h / Inert atmosphere; Reflux

2: iodine; caesium carbonate; N,N,N,N,N,N-hexamethylphosphoric triamide / 3 h / 80 °C

With N,N,N,N,N,N-hexamethylphosphoric triamide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; iodine; potassium carbonate; caesium carbonate; In ethanol; water; toluene;

DOI:10.1039/d0ob00433b

upstream raw materials:

2-nitro-11-phenyl-dibenzo[b,f][1,4]thiazepine

N-(4'-nitro-biphenyl-2-yl)-benzamide

2-(4-nitrophenyl)aniline

Benzotrichlorid

Downstream raw materials:

6-phenyl-phenanthridin-8-ylamine