Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Base Information

Chemical Name:Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate
CAS No.:251643-31-9
Molecular Formula:C₂₄H₂₉N₃O₈
Molecular Weight:487.51
Hs Code.:

Synonyms:Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Suppliers and Price of Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

There total 13 articles about Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 251643-16-0
methyl 2-(4-(methylamino)phenyl)acetate

: C₁₄H₁₇ClN₂O₆

: 251643-31-9
Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1039/a904067f

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 251643-31-9
Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Guidance literature:: Multi-step reaction with 5 steps

1: 97 percent / DMAP / tetrahydrofuran / 48 h / Heating

2: 99 percent / LiOH; H₂O / methanol / 0.5 h / 50 °C

3: 41 percent / BH₃*DMS / tetrahydrofuran / 3 h / 2 °C

4: benzene; tetrahydrofuran / 16 h / 20 °C

5: CS₂CO₃ / dimethylformamide / 16 h / 20 °C

With dmap; lithium hydroxide; dimethylsulfide borane complex; water; caesium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; benzene; 1: Substitution / 2: Hydrolysis / 3: Reduction / 4: Substitution / 5: Acylation;
DOI:10.1039/a904067f

Reference yield:

: 3558-13-2
4-nitro-2-methylaminobenzoic acid methyl ester

: 251643-31-9
Methyl 4-(N-methyl-N-{2-[N-methyl-N-(tert-butyloxycarbonyl)amino]-4-nitrobenzyloxycarbonyl}amino)phenylacetate

Guidance literature:: Multi-step reaction with 5 steps

1: 97 percent / DMAP / tetrahydrofuran / 48 h / Heating

2: 99 percent / LiOH; H₂O / methanol / 0.5 h / 50 °C

3: 41 percent / BH₃*DMS / tetrahydrofuran / 3 h / 2 °C

4: benzene; tetrahydrofuran / 16 h / 20 °C

5: CS₂CO₃ / dimethylformamide / 16 h / 20 °C

With dmap; lithium hydroxide; dimethylsulfide borane complex; water; caesium carbonate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; benzene; 1: Substitution / 2: Hydrolysis / 3: Reduction / 4: Substitution / 5: Acylation;
DOI:10.1039/a904067f